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Current drug discovery strategies for treatment of hepatitis C virus infection.
J Pharm Pharmacol. 2011 Jul;63(7):883-92. doi: 10.1111/j.2042-7158.2011.01267.x. Epub 2011 May 19.
J Pharm Pharmacol. 2011.
PMID: 21635253
Review.
Screening and rank ordering of reversible mechanism-based inhibitors of hepatitis C virus NS3 protease using electrospray ionization mass spectrometry.
Liu YH, Ramanathan L, Malcolm B, Njoroge G, Chan TY, Pramanik BN.
Liu YH, et al.
J Mass Spectrom. 2011 Aug;46(8):764-71. doi: 10.1002/jms.1948.
J Mass Spectrom. 2011.
PMID: 21766396
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Discovery of fused tricyclic core containing HCV NS5A inhibitors with pan-genotype activity.
Yu W, Coburn CA, Yang DY, Meinke PT, Wong M, Rosenblum SB, Chen KX, Njoroge GF, Chen L, Dwyer MP, Jiang Y, Nair AG, Selyutin O, Tong L, Zeng Q, Zhong B, Ji T, Hu B, Agrawal S, Xia E, Zhai Y, Liu R, Kong R, Ingravallo P, Asante-Appiah E, Nomeir A, Fells J, Kozlowski JA.
Yu W, et al. Among authors: njoroge gf.
Bioorg Med Chem Lett. 2016 Jul 1;26(13):3158-3162. doi: 10.1016/j.bmcl.2016.04.084. Epub 2016 Apr 30.
Bioorg Med Chem Lett. 2016.
PMID: 27180013
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I. Novel HCV NS5B polymerase inhibitors: discovery of indole 2-carboxylic acids with C3-heterocycles.
Anilkumar GN, Lesburg CA, Selyutin O, Rosenblum SB, Zeng Q, Jiang Y, Chan TY, Pu H, Vaccaro H, Wang L, Bennett F, Chen KX, Duca J, Gavalas S, Huang Y, Pinto P, Sannigrahi M, Velazquez F, Venkatraman S, Vibulbhan B, Agrawal S, Butkiewicz N, Feld B, Ferrari E, He Z, Jiang CK, Palermo RE, McMonagle P, Huang HC, Shih NY, Njoroge G, Kozlowski JA.
Anilkumar GN, et al.
Bioorg Med Chem Lett. 2011 Sep 15;21(18):5336-41. doi: 10.1016/j.bmcl.2011.07.021. Epub 2011 Jul 19.
Bioorg Med Chem Lett. 2011.
PMID: 21840715
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Discovery of C-imidazole azaheptapyridine FPT inhibitors.
Zhu HY, Cooper AB, Desai J, Njoroge G, Kirschmeier P, Bishop WR, Strickland C, Hruza A, Doll RJ, Girijavallabhan VM.
Zhu HY, et al.
Bioorg Med Chem Lett. 2010 Feb 1;20(3):1134-6. doi: 10.1016/j.bmcl.2009.12.013. Epub 2009 Dec 6.
Bioorg Med Chem Lett. 2010.
PMID: 20056542
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Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells.
Bishop WR, Bond R, Petrin J, Wang L, Patton R, Doll R, Njoroge G, Catino J, Schwartz J, Windsor W, et al.
Bishop WR, et al.
J Biol Chem. 1995 Dec 22;270(51):30611-8. doi: 10.1074/jbc.270.51.30611.
J Biol Chem. 1995.
PMID: 8530497
Free article.
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