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Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.
Innocenti F, Cooper GM, Stanaway IB, Gamazon ER, Smith JD, Mirkov S, Ramirez J, Liu W, Lin YS, Moloney C, Aldred SF, Trinklein ND, Schuetz E, Nickerson DA, Thummel KE, Rieder MJ, Rettie AE, Ratain MJ, Cox NJ, Brown CD. Innocenti F, et al. Among authors: aldred sf. PLoS Genet. 2011 May;7(5):e1002078. doi: 10.1371/journal.pgen.1002078. Epub 2011 May 26. PLoS Genet. 2011. PMID: 21637794 Free PMC article.
Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies.
Harris KE, Aldred SF, Davison LM, Ogana HAN, Boudreau A, Brüggemann M, Osborn M, Ma B, Buelow B, Clarke SC, Dang KH, Iyer S, Jorgensen B, Pham DT, Pratap PP, Rangaswamy US, Schellenberger U, van Schooten WC, Ugamraj HS, Vafa O, Buelow R, Trinklein ND. Harris KE, et al. Among authors: aldred sf. Front Immunol. 2018 Apr 24;9:889. doi: 10.3389/fimmu.2018.00889. eCollection 2018. Front Immunol. 2018. PMID: 29740455 Free PMC article.
When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions.
Bradbury ARM, Trinklein ND, Thie H, Wilkinson IC, Tandon AK, Anderson S, Bladen CL, Jones B, Aldred SF, Bestagno M, Burrone O, Maynard J, Ferrara F, Trimmer JS, Görnemann J, Glanville J, Wolf P, Frenzel A, Wong J, Koh XY, Eng HY, Lane D, Lefranc MP, Clark M, Dübel S. Bradbury ARM, et al. Among authors: aldred sf. MAbs. 2018 May/Jun;10(4):539-546. doi: 10.1080/19420862.2018.1445456. Epub 2018 Mar 29. MAbs. 2018. PMID: 29485921 Free PMC article.
Two-tiered approach identifies a network of cancer and liver disease-related genes regulated by miR-122.
Boutz DR, Collins PJ, Suresh U, Lu M, Ramírez CM, Fernández-Hernando C, Huang Y, Abreu Rde S, Le SY, Shapiro BA, Liu AM, Luk JM, Aldred SF, Trinklein ND, Marcotte EM, Penalva LO. Boutz DR, et al. Among authors: aldred sf. J Biol Chem. 2011 May 20;286(20):18066-78. doi: 10.1074/jbc.M110.196451. Epub 2011 Mar 14. J Biol Chem. 2011. PMID: 21402708 Free PMC article.
Identification of chemical compounds that induce HIF-1alpha activity.
Xia M, Huang R, Sun Y, Semenza GL, Aldred SF, Witt KL, Inglese J, Tice RR, Austin CP. Xia M, et al. Among authors: aldred sf. Toxicol Sci. 2009 Nov;112(1):153-63. doi: 10.1093/toxsci/kfp123. Epub 2009 Jun 5. Toxicol Sci. 2009. PMID: 19502547 Free PMC article.
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