Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

189 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
Shultz MD, Cao X, Chen CH, Cho YS, Davis NR, Eckman J, Fan J, Fekete A, Firestone B, Flynn J, Green J, Growney JD, Holmqvist M, Hsu M, Jansson D, Jiang L, Kwon P, Liu G, Lombardo F, Lu Q, Majumdar D, Meta C, Perez L, Pu M, Ramsey T, Remiszewski S, Skolnik S, Traebert M, Urban L, Uttamsingh V, Wang P, Whitebread S, Whitehead L, Yan-Neale Y, Yao YM, Zhou L, Atadja P. Shultz MD, et al. Among authors: eckman j. J Med Chem. 2011 Jul 14;54(13):4752-72. doi: 10.1021/jm200388e. Epub 2011 Jun 17. J Med Chem. 2011. PMID: 21650221
5-lipoxygenase inhibitors with histamine H(1) receptor antagonist activity.
Lewis TA, Bayless L, Eckman JB, Ellis JL, Grewal G, Libertine L, Marie Nicolas J, Scannell RT, Wels BF, Wenberg K, Wypij DM. Lewis TA, et al. Among authors: eckman jb. Bioorg Med Chem Lett. 2004 May 3;14(9):2265-8. doi: 10.1016/j.bmcl.2004.02.005. Bioorg Med Chem Lett. 2004. PMID: 15081022
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.
Cai X, Scannell RT, Yaeger D, Hussoin MS, Killian DB, Qian C, Eckman J, Hwang SB, Libertine-Garahan L, Yeh CG, Ip SH, Shen TY. Cai X, et al. Among authors: eckman j. J Med Chem. 1998 May 21;41(11):1970-9. doi: 10.1021/jm980046r. J Med Chem. 1998. PMID: 9599246
Novel dual acting molecules possessing 5-lipoxygenase enzyme inhibition and histamine H(1) receptor antagonist properties.
Scannell RT, Arrington MP, Bayless L, Cai X, Eckman JB, Eckert M, Ene DG, Ellis JL, Hussoin S, Latham GM, Lewis TA, Libertine L, Nicolas J, Selig WM, Schwartz CE, Wels BF, Wypij DM, Young MA, Zou D. Scannell RT, et al. Among authors: eckman jb. Inflamm Res. 2004 Mar;53 Suppl 1:S33-4. doi: 10.1007/s00011-003-0315-4. Epub 2004 Mar 5. Inflamm Res. 2004. PMID: 15054606 No abstract available.
Epibatidine is a nicotinic analgesic.
Qian C, Li T, Shen TY, Libertine-Garahan L, Eckman J, Biftu T, Ip S. Qian C, et al. Among authors: eckman j. Eur J Pharmacol. 1993 Dec 21;250(3):R13-4. doi: 10.1016/0014-2999(93)90043-h. Eur J Pharmacol. 1993. PMID: 8112391
189 results