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Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities.
Möllgård L, Saft L, Treppendahl MB, Dybedal I, Nørgaard JM, Astermark J, Ejerblad E, Garelius H, Dufva IH, Jansson M, Jädersten M, Kjeldsen L, Linder O, Nilsson L, Vestergaard H, Porwit A, Grønbæk K, Hellström-Lindberg E. Möllgård L, et al. Among authors: gronbaek k. Haematologica. 2011 Jul;96(7):963-71. doi: 10.3324/haematol.2010.039669. Haematologica. 2011. PMID: 21719884 Free PMC article. Clinical Trial.
Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML.
Treppendahl MB, Qiu X, Søgaard A, Yang X, Nandrup-Bus C, Hother C, Andersen MK, Kjeldsen L, Möllgård L, Hellström-Lindberg E, Jendholm J, Porse BT, Jones PA, Liang G, Grønbæk K. Treppendahl MB, et al. Among authors: gronbaek k. Blood. 2012 Jan 5;119(1):206-16. doi: 10.1182/blood-2011-06-362541. Epub 2011 Nov 4. Blood. 2012. PMID: 22058117 Free PMC article.
A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies.
Grønbæk K, Müller-Tidow C, Perini G, Lehmann S, Bach Treppendahl M, Mills K, Plass C, Schlegelberger B; European Genomics and Epigenomics Study on MDS and AML (EuGESMA), COST Action BM0801. Grønbæk K, et al. Haematologica. 2012 Sep;97(9):1380-8. doi: 10.3324/haematol.2011.058305. Epub 2012 Apr 4. Haematologica. 2012. PMID: 22491733 Free PMC article.
Analysis of epigenetic modifications of DNA in human cells.
Kristensen LS, Treppendahl MB, Grønbæk K. Kristensen LS, et al. Among authors: gronbaek k. Curr Protoc Hum Genet. 2013 Apr;Chapter 20:Unit20.2. doi: 10.1002/0471142905.hg2002s77. Curr Protoc Hum Genet. 2013. PMID: 23595599
Predicting response to epigenetic therapy.
Treppendahl MB, Kristensen LS, Grønbæk K. Treppendahl MB, et al. Among authors: gronbaek k. J Clin Invest. 2014 Jan;124(1):47-55. doi: 10.1172/JCI69737. Epub 2014 Jan 2. J Clin Invest. 2014. PMID: 24382389 Free PMC article. Review.
226 results