Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Search Results
7 results
Filters applied: . Clear all
Results are displayed in a computed author sort order.
The Results By Year timeline is not available.
Page 1
Phosphorylation of Y372 is critical for Jak2 tyrosine kinase activation.
Cell Signal. 2011 Nov;23(11):1806-15. doi: 10.1016/j.cellsig.2011.06.015. Epub 2011 Jun 29.
Cell Signal. 2011.
PMID: 21726629
Free PMC article.
A structure-function perspective of Jak2 mutations and implications for alternate drug design strategies: the road not taken.
Gnanasambandan K, Sayeski PP.
Gnanasambandan K, et al.
Curr Med Chem. 2011;18(30):4659-73. doi: 10.2174/092986711797379267.
Curr Med Chem. 2011.
PMID: 21864276
Free PMC article.
Review.
Item in Clipboard
The constitutive activation of Jak2-V617F is mediated by a π stacking mechanism involving phenylalanines 595 and 617.
Gnanasambandan K, Magis A, Sayeski PP.
Gnanasambandan K, et al.
Biochemistry. 2010 Nov 23;49(46):9972-84. doi: 10.1021/bi1014858. Epub 2010 Oct 29.
Biochemistry. 2010.
PMID: 20958061
Free PMC article.
Item in Clipboard
A shift in the salt bridge interaction of residues D620 and E621 mediates the constitutive activation of Jak2-H538Q/K539L.
Gnanasambandan K, Magis AT, Sayeski PP.
Gnanasambandan K, et al.
Mol Cell Biochem. 2012 Aug;367(1-2):125-40. doi: 10.1007/s11010-012-1326-7. Epub 2012 May 15.
Mol Cell Biochem. 2012.
PMID: 22584586
Item in Clipboard
Whole-exome sequencing in evaluation of patients with venous thromboembolism.
Lee EJ, Dykas DJ, Leavitt AD, Camire RM, Ebberink E, García de Frutos P, Gnanasambandan K, Gu SX, Huntington JA, Lentz SR, Mertens K, Parish CR, Rezaie AR, Sayeski PP, Cromwell C, Bar N, Halene S, Neparidze N, Parker TL, Burns AJ, Dumont A, Yao X, Chaar CIO, Connors JM, Bale AE, Lee AI.
Lee EJ, et al. Among authors: gnanasambandan k.
Blood Adv. 2017 Jun 29;1(16):1224-1237. doi: 10.1182/bloodadvances.2017005249. eCollection 2017 Jul 11.
Blood Adv. 2017.
PMID: 29296762
Free PMC article.
Item in Clipboard
Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase.
Shan Y, Gnanasambandan K, Ungureanu D, Kim ET, Hammarén H, Yamashita K, Silvennoinen O, Shaw DE, Hubbard SR.
Shan Y, et al. Among authors: gnanasambandan k.
Nat Struct Mol Biol. 2014 Jul;21(7):579-84. doi: 10.1038/nsmb.2849. Epub 2014 Jun 11.
Nat Struct Mol Biol. 2014.
PMID: 24918548
Free PMC article.
Item in Clipboard
Structure and activation of MuSK, a receptor tyrosine kinase central to neuromuscular junction formation.
Hubbard SR, Gnanasambandan K.
Hubbard SR, et al. Among authors: gnanasambandan k.
Biochim Biophys Acta. 2013 Oct;1834(10):2166-9. doi: 10.1016/j.bbapap.2013.02.034. Epub 2013 Mar 5.
Biochim Biophys Acta. 2013.
PMID: 23467009
Free PMC article.
Review.
Item in Clipboard
Cite
Cite