Nathan JA - Search Results

1

Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry.

Deriziotis P, André R, Smith DM, Goold R, Kinghorn KJ, Kristiansen M, Nathan JA, Rosenzweig R, Krutauz D, Glickman MH, Collinge J, Goldberg AL, Tabrizi SJ. Deriziotis P, et al. Among authors: nathan ja. EMBO J. 2011 Jul 8;30(15):3065-77. doi: 10.1038/emboj.2011.224. EMBO J. 2011. PMID: 21743439 Free PMC article.

2

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

Nathan JA, Kim HT, Ting L, Gygi SP, Goldberg AL. Nathan JA, et al. EMBO J. 2013 Feb 20;32(4):552-65. doi: 10.1038/emboj.2012.354. Epub 2013 Jan 11. EMBO J. 2013. PMID: 23314748 Free PMC article.

3

Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins.

Nathan JA, Spinnenhirn V, Schmidtke G, Basler M, Groettrup M, Goldberg AL. Nathan JA, et al. Cell. 2013 Feb 28;152(5):1184-94. doi: 10.1016/j.cell.2013.01.037. Cell. 2013. PMID: 23452861 Free PMC article.

4

The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome.

Peth A, Nathan JA, Goldberg AL. Peth A, et al. Among authors: nathan ja. J Biol Chem. 2013 Oct 4;288(40):29215-22. doi: 10.1074/jbc.M113.482570. Epub 2013 Aug 21. J Biol Chem. 2013. PMID: 23965995 Free PMC article.

5

Muscle wasting in disease: molecular mechanisms and promising therapies.

Cohen S, Nathan JA, Goldberg AL. Cohen S, et al. Among authors: nathan ja. Nat Rev Drug Discov. 2015 Jan;14(1):58-74. doi: 10.1038/nrd4467. Nat Rev Drug Discov. 2015. PMID: 25549588 Review.

6

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.

Stefanovic-Barrett S, Dickson AS, Burr SP, Williamson JC, Lobb IT, van den Boomen DJ, Lehner PJ, Nathan JA. Stefanovic-Barrett S, et al. Among authors: nathan ja. EMBO Rep. 2018 May;19(5):e45603. doi: 10.15252/embr.201745603. Epub 2018 Mar 8. EMBO Rep. 2018. PMID: 29519897 Free PMC article.

7

APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS.

Signes A, Cerutti R, Dickson AS, Benincá C, Hinchy EC, Ghezzi D, Carrozzo R, Bertini E, Murphy MP, Nathan JA, Viscomi C, Fernandez-Vizarra E, Zeviani M. Signes A, et al. Among authors: nathan ja. EMBO Mol Med. 2019 Jan;11(1):e9582. doi: 10.15252/emmm.201809582. EMBO Mol Med. 2019. PMID: 30552096 Free PMC article.

8

The recognition of ubiquitinated proteins by the proteasome.

Grice GL, Nathan JA. Grice GL, et al. Among authors: nathan ja. Cell Mol Life Sci. 2016 Sep;73(18):3497-506. doi: 10.1007/s00018-016-2255-5. Epub 2016 May 2. Cell Mol Life Sci. 2016. PMID: 27137187 Free PMC article. Review.

9

Limited oxygen in standard cell culture alters metabolism and function of differentiated cells.

Tan J, Virtue S, Norris DM, Conway OJ, Yang M, Bidault G, Gribben C, Lugtu F, Kamzolas I, Krycer JR, Mills RJ, Liang L, Pereira C, Dale M, Shun-Shion AS, Baird HJ, Horscroft JA, Sowton AP, Ma M, Carobbio S, Petsalaki E, Murray AJ, Gershlick DC, Nathan JA, Hudson JE, Vallier L, Fisher-Wellman KH, Frezza C, Vidal-Puig A, Fazakerley DJ. Tan J, et al. Among authors: nathan ja. EMBO J. 2024 Apr 5. doi: 10.1038/s44318-024-00084-7. Online ahead of print. EMBO J. 2024. PMID: 38580776 Free article.

10

Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression.

Duncan LM, Nathan JA, Lehner PJ. Duncan LM, et al. Among authors: nathan ja. J Immunol. 2010 Jun 15;184(12):6978-85. doi: 10.4049/jimmunol.0904154. Epub 2010 May 12. J Immunol. 2010. PMID: 20483773 Free PMC article.

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