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Systems medicine and integrated care to combat chronic noncommunicable diseases.
Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C. Bousquet J, et al. Among authors: fabbri l. Genome Med. 2011 Jul 6;3(7):43. doi: 10.1186/gm259. Genome Med. 2011. PMID: 21745417 Free PMC article.
Systems medicine approaches for the definition of complex phenotypes in chronic diseases and ageing. From concept to implementation and policies.
Bousquet J, Jorgensen C, Dauzat M, Cesario A, Camuzat T, Bourret R, Best N, Anto JM, Abecassis F, Aubas P, Avignon A, Badin M, Bedbrook A, Blain H, Bourdin A, Bringer J, Camu W, Cayla G, Costa DJ, Courtet P, Cristol JP, Demoly P, de la Coussaye JE, Fesler P, Gouzi F, Gris JC, Guillot B, Hayot M, Jeandel C, Jonquet O, Journot L, Lehmann S, Mathieu G, Morel J, Ninot G, Pelissier J, Picot MC, Radier-Pontal F, Robine JM, Rodier M, Roubille F, Sultan A, Wojtusciszyn A, Auffray C, Balling R, Barbara C, Cambon-Thomsen A, Chavannes NH, Chuchalin A, Crooks G, Dedeu A, Fabbri LM, Garcia-Aymerich J, Hajjam J, Melo Gomes E, Palkonen S, Piette F, Pison C, Price D, Samolinski B, Schunemann HJ, Sterk PJ, Yiallouros P, Roca J, Van de Perre P, Mercier J. Bousquet J, et al. Among authors: fabbri lm. Curr Pharm Des. 2014;20(38):5928-44. doi: 10.2174/1381612820666140314115505. Curr Pharm Des. 2014. PMID: 24641234 Review.
Should we use gait speed in COPD, FEV1 in frailty and dyspnoea in both?
Bousquet J, Dinh-Xuan AT, Similowski T, Malva J, Ankri J, Barbagallo M, Fabbri L, Humbert M, Mercier J, Robalo-Cordeiro C, Rodriguez-Manas L, Vellas B. Bousquet J, et al. Among authors: fabbri l. Eur Respir J. 2016 Aug;48(2):315-9. doi: 10.1183/13993003.00633-2016. Eur Respir J. 2016. PMID: 27478189 Free article. No abstract available.
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease.
Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters EF, Agustí A, Fabbri LM, Rames A, Visvanathan S, Rennard SI, Jones P, Parmar H, MacNee W, Wolff G, Silverman EK, Mayer RJ, Pillai SG; TESRA and ECLIPSE Investigators. Cheng DT, et al. Am J Respir Crit Care Med. 2013 Oct 15;188(8):948-57. doi: 10.1164/rccm.201302-0247OC. Am J Respir Crit Care Med. 2013. PMID: 23947473
Montelukast or salmeterol combined with an inhaled steroid in adult asthma: design and rationale of a randomized, double-blind comparative study (the IMPACT Investigation of Montelukast as a Partner Agent for Complementary Therapy-trial).
Bjermer L, Bisgaard H, Bousquet J, Fabbri LM, Greening A, Haahtela T, Holgate ST, Picado C, Leff JA. Bjermer L, et al. Among authors: fabbri lm. Respir Med. 2000 Jun;94(6):612-21. doi: 10.1053/rmed.2000.0806. Respir Med. 2000. PMID: 10921768 Free article. Clinical Trial.
Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial.
Papi A, Vestbo J, Fabbri L, Corradi M, Prunier H, Cohuet G, Guasconi A, Montagna I, Vezzoli S, Petruzzelli S, Scuri M, Roche N, Singh D. Papi A, et al. Among authors: fabbri l. Lancet. 2018 Mar 17;391(10125):1076-1084. doi: 10.1016/S0140-6736(18)30206-X. Epub 2018 Feb 9. Lancet. 2018. PMID: 29429593 Clinical Trial.
970 results