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Prediction of a potentially effective dose in humans for BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically-based pharmacokinetic modelling.
Weber O, Willmann S, Bischoff H, Li V, Vakalopoulos A, Lustig K, Hafner FT, Heinig R, Schmeck C, Buehner K. Weber O, et al. Among authors: buehner k. Br J Clin Pharmacol. 2012 Feb;73(2):219-31. doi: 10.1111/j.1365-2125.2011.04064.x. Br J Clin Pharmacol. 2012. PMID: 21762205 Free PMC article.
Pharmacokinetics of repinotan in healthy and brain injured animals.
Schwarz T, Beckermann B, Buehner K, Mauler F, Schuhmacher J, Seidel D, Steinke W, Weinz C, Zimmerd D. Schwarz T, et al. Among authors: buehner k. Biopharm Drug Dispos. 2005 Sep;26(6):259-68. doi: 10.1002/bdd.458. Biopharm Drug Dispos. 2005. PMID: 15966026