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Page 1
Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth.
Han Y, Demorrow S, Invernizzi P, Jing Q, Glaser S, Renzi A, Meng F, Venter J, Bernuzzi F, White M, Francis H, Lleo A, Marzioni M, Onori P, Alvaro D, Torzilli G, Gaudio E, Alpini G. Han Y, et al. Among authors: white m. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G623-33. doi: 10.1152/ajpgi.00118.2011. Epub 2011 Jul 21. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21778461 Free PMC article.
Follicle-stimulating hormone increases cholangiocyte proliferation by an autocrine mechanism via cAMP-dependent phosphorylation of ERK1/2 and Elk-1.
Mancinelli R, Onori P, Gaudio E, DeMorrow S, Franchitto A, Francis H, Glaser S, Carpino G, Venter J, Alvaro D, Kopriva S, White M, Kossie A, Savage J, Alpini G. Mancinelli R, et al. Among authors: white m. Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G11-26. doi: 10.1152/ajpgi.00025.2009. Epub 2009 Apr 23. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19389804 Free PMC article.
Neuropeptide Y inhibits cholangiocarcinoma cell growth and invasion.
DeMorrow S, Onori P, Venter J, Invernizzi P, Frampton G, White M, Franchitto A, Kopriva S, Bernuzzi F, Francis H, Coufal M, Glaser S, Fava G, Meng F, Alvaro D, Carpino G, Gaudio E, Alpini G. DeMorrow S, et al. Among authors: white m. Am J Physiol Cell Physiol. 2011 May;300(5):C1078-89. doi: 10.1152/ajpcell.00358.2010. Epub 2011 Jan 26. Am J Physiol Cell Physiol. 2011. PMID: 21270292 Free PMC article.
Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice.
Glaser S, Gaudio E, Renzi A, Mancinelli R, Ueno Y, Venter J, White M, Kopriva S, Chiasson V, DeMorrow S, Francis H, Meng F, Marzioni M, Franchitto A, Alvaro D, Supowit S, DiPette DJ, Onori P, Alpini G. Glaser S, et al. Among authors: white m. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G297-305. doi: 10.1152/ajpgi.00418.2010. Epub 2011 May 19. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21596993 Free PMC article.
Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.
Renzi A, Glaser S, Demorrow S, Mancinelli R, Meng F, Franchitto A, Venter J, White M, Francis H, Han Y, Alvaro D, Gaudio E, Carpino G, Ueno Y, Onori P, Alpini G. Renzi A, et al. Among authors: white m. Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G634-43. doi: 10.1152/ajpgi.00206.2011. Epub 2011 Jul 14. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21757639 Free PMC article.
Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats.
Renzi A, DeMorrow S, Onori P, Carpino G, Mancinelli R, Meng F, Venter J, White M, Franchitto A, Francis H, Han Y, Ueno Y, Dusio G, Jensen KJ, Greene JJ Jr, Glaser S, Gaudio E, Alpini G. Renzi A, et al. Among authors: white m. Hepatology. 2013 Mar;57(3):1130-41. doi: 10.1002/hep.26105. Epub 2013 Feb 7. Hepatology. 2013. PMID: 23080076 Free PMC article.
Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms.
Francis HL, Demorrow S, Franchitto A, Venter JK, Mancinelli RA, White MA, Meng F, Ueno Y, Carpino G, Renzi A, Baker KK, Shine HE, Francis TC, Gaudio E, Alpini GD, Onori P. Francis HL, et al. Lab Invest. 2012 Feb;92(2):282-94. doi: 10.1038/labinvest.2011.158. Epub 2011 Nov 7. Lab Invest. 2012. PMID: 22064319 Free PMC article.
H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo.
Francis H, Onori P, Gaudio E, Franchitto A, DeMorrow S, Venter J, Kopriva S, Carpino G, Mancinelli R, White M, Meng F, Vetuschi A, Sferra R, Alpini G. Francis H, et al. Among authors: white m. Mol Cancer Res. 2009 Oct;7(10):1704-13. doi: 10.1158/1541-7786.MCR-09-0261. Epub 2009 Oct 13. Mol Cancer Res. 2009. PMID: 19825989 Free PMC article.
After damage of large bile ducts by gamma-aminobutyric acid, small ducts replenish the biliary tree by amplification of calcium-dependent signaling and de novo acquisition of large cholangiocyte phenotypes.
Mancinelli R, Franchitto A, Gaudio E, Onori P, Glaser S, Francis H, Venter J, Demorrow S, Carpino G, Kopriva S, White M, Fava G, Alvaro D, Alpini G. Mancinelli R, et al. Among authors: white m. Am J Pathol. 2010 Apr;176(4):1790-800. doi: 10.2353/ajpath.2010.090677. Epub 2010 Feb 25. Am J Pathol. 2010. PMID: 20185575 Free PMC article.
7,510 results