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Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice.
Coombes JD, Swiderska-Syn M, Dollé L, Reid D, Eksteen B, Claridge L, Briones-Orta MA, Shetty S, Oo YH, Riva A, Chokshi S, Papa S, Mi Z, Kuo PC, Williams R, Canbay A, Adams DH, Diehl AM, van Grunsven LA, Choi SS, Syn WK. Coombes JD, et al. Gut. 2015 Jul;64(7):1120-31. doi: 10.1136/gutjnl-2013-306484. Epub 2014 Jun 5. Gut. 2015. PMID: 24902765 Free PMC article.
Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis.
Coombes JD, Choi SS, Swiderska-Syn M, Manka P, Reid DT, Palma E, Briones-Orta MA, Xie G, Younis R, Kitamura N, Della Peruta M, Bitencourt S, Dollé L, Oo YH, Mi Z, Kuo PC, Williams R, Chokshi S, Canbay A, Claridge LC, Eksteen B, Diehl AM, Syn WK. Coombes JD, et al. Among authors: claridge lc. Biochim Biophys Acta. 2016 Jan;1862(1):135-44. doi: 10.1016/j.bbadis.2015.10.028. Epub 2015 Oct 31. Biochim Biophys Acta. 2016. PMID: 26529285 Free PMC article.
Gilbert's syndrome.
Claridge LC, Armstrong MJ, Booth C, Gill PS. Claridge LC, et al. BMJ. 2011 Apr 19;342:d2293. doi: 10.1136/bmj.d2293. BMJ. 2011. PMID: 21508045 No abstract available.
Dysregulated hepatic expression of glucose transporters in chronic disease: contribution of semicarbazide-sensitive amine oxidase to hepatic glucose uptake.
Karim S, Liaskou E, Fear J, Garg A, Reynolds G, Claridge L, Adams DH, Newsome PN, Lalor PF. Karim S, et al. Am J Physiol Gastrointest Liver Physiol. 2014 Dec 15;307(12):G1180-90. doi: 10.1152/ajpgi.00377.2013. Epub 2014 Oct 23. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 25342050 Free PMC article.
Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.
Weston CJ, Shepherd EL, Claridge LC, Rantakari P, Curbishley SM, Tomlinson JW, Hubscher SG, Reynolds GM, Aalto K, Anstee QM, Jalkanen S, Salmi M, Smith DJ, Day CP, Adams DH. Weston CJ, et al. Among authors: claridge lc. J Clin Invest. 2015 Feb;125(2):501-20. doi: 10.1172/JCI73722. Epub 2014 Dec 22. J Clin Invest. 2015. PMID: 25562318 Free PMC article. Clinical Trial.
19 results