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Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue.
Devine MJ, Kaganovich A, Ryten M, Mamais A, Trabzuni D, Manzoni C, McGoldrick P, Chan D, Dillman A, Zerle J, Horan S, Taanman JW, Hardy J, Marti-Masso JF, Healy D, Schapira AH, Wolozin B, Bandopadhyay R, Cookson MR, van der Brug MP, Lewis PA. Devine MJ, et al. Among authors: hardy j. PLoS One. 2011;6(7):e22489. doi: 10.1371/journal.pone.0022489. Epub 2011 Jul 22. PLoS One. 2011. PMID: 21799870 Free PMC article.
Genes and parkinsonism.
Hardy J, Cookson MR, Singleton A. Hardy J, et al. Lancet Neurol. 2003 Apr;2(4):221-8. doi: 10.1016/s1474-4422(03)00350-8. Lancet Neurol. 2003. PMID: 12849210 Review.
Genetics of Parkinson's disease and parkinsonism.
Hardy J, Cai H, Cookson MR, Gwinn-Hardy K, Singleton A. Hardy J, et al. Ann Neurol. 2006 Oct;60(4):389-98. doi: 10.1002/ana.21022. Ann Neurol. 2006. PMID: 17068789 Review.
The persistence of memory.
Cookson MR, Hardy J. Cookson MR, et al. Among authors: hardy j. N Engl J Med. 2006 Dec 21;355(25):2697-8. doi: 10.1056/NEJMcibr065999. N Engl J Med. 2006. PMID: 17182998 No abstract available.
Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans.
van de Leemput J, Chandran J, Knight MA, Holtzclaw LA, Scholz S, Cookson MR, Houlden H, Gwinn-Hardy K, Fung HC, Lin X, Hernandez D, Simon-Sanchez J, Wood NW, Giunti P, Rafferty I, Hardy J, Storey E, Gardner RJ, Forrest SM, Fisher EM, Russell JT, Cai H, Singleton AB. van de Leemput J, et al. Among authors: hardy j. PLoS Genet. 2007 Jun;3(6):e108. doi: 10.1371/journal.pgen.0030108. Epub 2007 May 16. PLoS Genet. 2007. PMID: 17590087 Free PMC article.
Genetic neuropathology of Parkinson's disease.
Cookson MR, Hardy J, Lewis PA. Cookson MR, et al. Among authors: hardy j. Int J Clin Exp Pathol. 2008 Jan 1;1(3):217-31. Int J Clin Exp Pathol. 2008. PMID: 18784814 Free PMC article.
Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease.
Neumann J, Bras J, Deas E, O'Sullivan SS, Parkkinen L, Lachmann RH, Li A, Holton J, Guerreiro R, Paudel R, Segarane B, Singleton A, Lees A, Hardy J, Houlden H, Revesz T, Wood NW. Neumann J, et al. Among authors: hardy j. Brain. 2009 Jul;132(Pt 7):1783-94. doi: 10.1093/brain/awp044. Epub 2009 Mar 13. Brain. 2009. PMID: 19286695 Free PMC article.
The genetics of Parkinson's syndromes: a critical review.
Hardy J, Lewis P, Revesz T, Lees A, Paisan-Ruiz C. Hardy J, et al. Curr Opin Genet Dev. 2009 Jun;19(3):254-65. doi: 10.1016/j.gde.2009.03.008. Epub 2009 May 4. Curr Opin Genet Dev. 2009. PMID: 19419854 Review.
3,438 results