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Identifying the proteins to which small-molecule probes and drugs bind in cells.
Ong SE, Schenone M, Margolin AA, Li X, Do K, Doud MK, Mani DR, Kuai L, Wang X, Wood JL, Tolliday NJ, Koehler AN, Marcaurelle LA, Golub TR, Gould RJ, Schreiber SL, Carr SA. Ong SE, et al. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4617-22. doi: 10.1073/pnas.0900191106. Epub 2009 Mar 2. Proc Natl Acad Sci U S A. 2009. PMID: 19255428 Free PMC article.
Empirical Bayes analysis of quantitative proteomics experiments.
Margolin AA, Ong SE, Schenone M, Gould R, Schreiber SL, Carr SA, Golub TR. Margolin AA, et al. Among authors: ong se. PLoS One. 2009 Oct 14;4(10):e7454. doi: 10.1371/journal.pone.0007454. PLoS One. 2009. PMID: 19829701 Free PMC article.
A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.
van Vugt MA, Gardino AK, Linding R, Ostheimer GJ, Reinhardt HC, Ong SE, Tan CS, Miao H, Keezer SM, Li J, Pawson T, Lewis TA, Carr SA, Smerdon SJ, Brummelkamp TR, Yaffe MB. van Vugt MA, et al. Among authors: ong se. PLoS Biol. 2010 Jan 26;8(1):e1000287. doi: 10.1371/journal.pbio.1000287. PLoS Biol. 2010. PMID: 20126263 Free PMC article.
Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells.
Jin YN, Schlueter PJ, Jurisch-Yaksi N, Lam PY, Jin S, Hwang WY, Yeh JJ, Yoshigi M, Ong SE, Schenone M, Hartigan CR, Carr SA, Peterson RT. Jin YN, et al. Among authors: ong se. Nat Chem Biol. 2018 Sep;14(9):844-852. doi: 10.1038/s41589-018-0098-0. Epub 2018 Jul 9. Nat Chem Biol. 2018. PMID: 29988067 Free PMC article.
106 results