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G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes.
Trégouet DA, Groop PH, McGinn S, Forsblom C, Hadjadj S, Marre M, Parving HH, Tarnow L, Telgmann R, Godefroy T, Nicaud V, Rousseau R, Parkkonen M, Hoverfält A, Gut I, Heath S, Matsuda F, Cox R, Kazeem G, Farrall M, Gauguier D, Brand-Herrmann SM, Cambien F, Lathrop M, Vionnet N; EURAGEDIC Consortium. Trégouet DA, et al. Among authors: lathrop m. Diabetes. 2008 Oct;57(10):2843-50. doi: 10.2337/db08-0073. Epub 2008 Jul 15. Diabetes. 2008. PMID: 18633107 Free PMC article.
Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach.
Trégouët DA, Heath S, Saut N, Biron-Andreani C, Schved JF, Pernod G, Galan P, Drouet L, Zelenika D, Juhan-Vague I, Alessi MC, Tiret L, Lathrop M, Emmerich J, Morange PE. Trégouët DA, et al. Among authors: lathrop m. Blood. 2009 May 21;113(21):5298-303. doi: 10.1182/blood-2008-11-190389. Epub 2009 Mar 10. Blood. 2009. PMID: 19278955 Free article.
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fiévet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O; European Alzheimer's Disease Initiative Investigators; de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanché H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alpérovitch A, Lathrop M, Amouyel P. Lambert JC, et al. Among authors: lathrop m. Nat Genet. 2009 Oct;41(10):1094-9. doi: 10.1038/ng.439. Epub 2009 Sep 6. Nat Genet. 2009. PMID: 19734903 Free article.
C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies.
Buil A, Trégouët DA, Souto JC, Saut N, Germain M, Rotival M, Tiret L, Cambien F, Lathrop M, Zeller T, Alessi MC, Rodriguez de Cordoba S, Münzel T, Wild P, Fontcuberta J, Gagnon F, Emmerich J, Almasy L, Blankenberg S, Soria JM, Morange PE. Buil A, et al. Among authors: lathrop m. Blood. 2010 Jun 10;115(23):4644-50. doi: 10.1182/blood-2010-01-263038. Epub 2010 Mar 8. Blood. 2010. PMID: 20212171 Free PMC article.
A follow-up study of a genome-wide association scan identifies a susceptibility locus for venous thrombosis on chromosome 6p24.1.
Morange PE, Bezemer I, Saut N, Bare L, Burgos G, Brocheton J, Durand H, Biron-Andreani C, Schved JF, Pernod G, Galan P, Drouet L, Zelenika D, Germain M, Nicaud V, Heath S, Ninio E, Delluc A, Münzel T, Zeller T, Brand-Herrmann SM, Alessi MC, Tiret L, Lathrop M, Cambien F, Blankenberg S, Emmerich J, Trégouët DA, Rosendaal FR. Morange PE, et al. Among authors: lathrop m. Am J Hum Genet. 2010 Apr 9;86(4):592-5. doi: 10.1016/j.ajhg.2010.02.011. Epub 2010 Mar 11. Am J Hum Genet. 2010. PMID: 20226436 Free PMC article.
Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study.
Laumet G, Chouraki V, Grenier-Boley B, Legry V, Heath S, Zelenika D, Fievet N, Hannequin D, Delepine M, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Bertram L, Amouyel P, Lambert JC. Laumet G, et al. Among authors: lathrop m. J Alzheimers Dis. 2010;20(4):1181-8. doi: 10.3233/JAD-2010-100126. J Alzheimers Dis. 2010. PMID: 20413850
Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.
Saad M, Lesage S, Saint-Pierre A, Corvol JC, Zelenika D, Lambert JC, Vidailhet M, Mellick GD, Lohmann E, Durif F, Pollak P, Damier P, Tison F, Silburn PA, Tzourio C, Forlani S, Loriot MA, Giroud M, Helmer C, Portet F, Amouyel P, Lathrop M, Elbaz A, Durr A, Martinez M, Brice A; French Parkinson's Disease Genetics Study Group. Saad M, et al. Among authors: lathrop m. Hum Mol Genet. 2011 Feb 1;20(3):615-27. doi: 10.1093/hmg/ddq497. Epub 2010 Nov 17. Hum Mol Genet. 2011. PMID: 21084426
KNG1 Ile581Thr and susceptibility to venous thrombosis.
Morange PE, Oudot-Mellakh T, Cohen W, Germain M, Saut N, Antoni G, Alessi MC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Lopez LM, Lambert JC, Emmerich J, Amouyel P, Trégouët DA. Morange PE, et al. Among authors: lathrop m. Blood. 2011 Mar 31;117(13):3692-4. doi: 10.1182/blood-2010-11-319053. Epub 2011 Jan 26. Blood. 2011. PMID: 21270443 Free article.
Genome-wide association study of HPV seropositivity.
Chen D, McKay JD, Clifford G, Gaborieau V, Chabrier A, Waterboer T, Zaridze D, Lissowska J, Rudnai P, Fabianova E, Bencko V, Janout V, Foretova L, Mates IN, Szeszenia-Dabrowska N, Curado MP, Koifman S, Menezes A, Wünsch-Filho V, Eluf-Neto J, Fernández Garrote L, Matos E, Zelenika D, Boland A, Boffetta P, Pawlita M, Lathrop M, Brennan P. Chen D, et al. Among authors: lathrop m. Hum Mol Genet. 2011 Dec 1;20(23):4714-23. doi: 10.1093/hmg/ddr383. Epub 2011 Sep 6. Hum Mol Genet. 2011. PMID: 21896673
658 results