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Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality.
Chan DA, Sutphin PD, Nguyen P, Turcotte S, Lai EW, Banh A, Reynolds GE, Chi JT, Wu J, Solow-Cordero DE, Bonnet M, Flanagan JU, Bouley DM, Graves EE, Denny WA, Hay MP, Giaccia AJ. Chan DA, et al. Among authors: bouley dm. Sci Transl Med. 2011 Aug 3;3(94):94ra70. doi: 10.1126/scitranslmed.3002394. Sci Transl Med. 2011. PMID: 21813754 Free PMC article.
Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.
Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Matheny CJ, et al. Among authors: bouley dm. Chem Biol. 2013 Nov 21;20(11):1352-63. doi: 10.1016/j.chembiol.2013.09.014. Epub 2013 Oct 31. Chem Biol. 2013. PMID: 24183972 Free PMC article.
Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice.
Bedogni B, O'Neill MS, Welford SM, Bouley DM, Giaccia AJ, Denko NC, Powell MB. Bedogni B, et al. Among authors: bouley dm. Cancer Res. 2004 Apr 1;64(7):2552-60. doi: 10.1158/0008-5472.can-03-3327. Cancer Res. 2004. PMID: 15059911
94 results