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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.
Fehrmann RS, Jansen RC, Veldink JH, Westra HJ, Arends D, Bonder MJ, Fu J, Deelen P, Groen HJ, Smolonska A, Weersma RK, Hofstra RM, Buurman WA, Rensen S, Wolfs MG, Platteel M, Zhernakova A, Elbers CC, Festen EM, Trynka G, Hofker MH, Saris CG, Ophoff RA, van den Berg LH, van Heel DA, Wijmenga C, Te Meerman GJ, Franke L. Fehrmann RS, et al. Among authors: wolfs mg. PLoS Genet. 2011 Aug;7(8):e1002197. doi: 10.1371/journal.pgen.1002197. Epub 2011 Aug 4. PLoS Genet. 2011. PMID: 21829388 Free PMC article.
Genetic and epigenetic regulation of gene expression in fetal and adult human livers.
Bonder MJ, Kasela S, Kals M, Tamm R, Lokk K, Barragan I, Buurman WA, Deelen P, Greve JW, Ivanov M, Rensen SS, van Vliet-Ostaptchouk JV, Wolfs MG, Fu J, Hofker MH, Wijmenga C, Zhernakova A, Ingelman-Sundberg M, Franke L, Milani L. Bonder MJ, et al. Among authors: wolfs mg. BMC Genomics. 2014 Oct 4;15(1):860. doi: 10.1186/1471-2164-15-860. BMC Genomics. 2014. PMID: 25282492 Free PMC article.
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression.
Fu J, Wolfs MG, Deelen P, Westra HJ, Fehrmann RS, Te Meerman GJ, Buurman WA, Rensen SS, Groen HJ, Weersma RK, van den Berg LH, Veldink J, Ophoff RA, Snieder H, van Heel D, Jansen RC, Hofker MH, Wijmenga C, Franke L. Fu J, et al. Among authors: wolfs mg. PLoS Genet. 2012 Jan;8(1):e1002431. doi: 10.1371/journal.pgen.1002431. Epub 2012 Jan 19. PLoS Genet. 2012. PMID: 22275870 Free PMC article.
Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray study.
Wolfs MG, Rensen SS, Bruin-Van Dijk EJ, Verdam FJ, Greve JW, Sanjabi B, Bruinenberg M, Wijmenga C, van Haeften TW, Buurman WA, Franke L, Hofker MH. Wolfs MG, et al. BMC Med Genomics. 2010 Aug 5;3:34. doi: 10.1186/1755-8794-3-34. BMC Med Genomics. 2010. PMID: 20687939 Free PMC article.
TUB gene expression in hypothalamus and adipose tissue and its association with obesity in humans.
Nies VJM, Struik D, Wolfs MGM, Rensen SS, Szalowska E, Unmehopa UA, Fluiter K, van der Meer TP, Hajmousa G, Buurman WA, Greve JW, Rezaee F, Shiri-Sverdlov R, Vonk RJ, Swaab DF, Wolffenbuttel BHR, Jonker JW, van Vliet-Ostaptchouk JV. Nies VJM, et al. Among authors: wolfs mgm. Int J Obes (Lond). 2018 Mar;42(3):376-383. doi: 10.1038/ijo.2017.214. Epub 2017 Aug 30. Int J Obes (Lond). 2018. PMID: 28852204
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