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Site-specific integration and tailoring of cassette design for sustainable gene transfer.
Lombardo A, Cesana D, Genovese P, Di Stefano B, Provasi E, Colombo DF, Neri M, Magnani Z, Cantore A, Lo Riso P, Damo M, Pello OM, Holmes MC, Gregory PD, Gritti A, Broccoli V, Bonini C, Naldini L. Lombardo A, et al. Among authors: broccoli v. Nat Methods. 2011 Aug 21;8(10):861-9. doi: 10.1038/nmeth.1674. Nat Methods. 2011. PMID: 21857672
An ES-like pluripotent state in FGF-dependent murine iPS cells.
Di Stefano B, Buecker C, Ungaro F, Prigione A, Chen HH, Welling M, Eijpe M, Mostoslavsky G, Tesar P, Adjaye J, Geijsen N, Broccoli V. Di Stefano B, et al. Among authors: broccoli v. PLoS One. 2010 Dec 30;5(12):e16092. doi: 10.1371/journal.pone.0016092. PLoS One. 2010. PMID: 21209851 Free PMC article.
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts.
Caiazzo M, Dell'Anno MT, Dvoretskova E, Lazarevic D, Taverna S, Leo D, Sotnikova TD, Menegon A, Roncaglia P, Colciago G, Russo G, Carninci P, Pezzoli G, Gainetdinov RR, Gustincich S, Dityatev A, Broccoli V. Caiazzo M, et al. Among authors: broccoli v. Nature. 2011 Jul 3;476(7359):224-7. doi: 10.1038/nature10284. Nature. 2011. PMID: 21725324
Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.
Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, Di Stefano B, Mantegazza R, Broccoli V, Böckers TM, Dityatev A, Sala C. Verpelli C, et al. Among authors: broccoli v. J Biol Chem. 2011 Oct 7;286(40):34839-50. doi: 10.1074/jbc.M111.258384. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795692 Free PMC article.
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells.
Mazzara PG, Massimino L, Pellegatta M, Ronchi G, Ricca A, Iannielli A, Giannelli SG, Cursi M, Cancellieri C, Sessa A, Del Carro U, Quattrini A, Geuna S, Gritti A, Taveggia C, Broccoli V. Mazzara PG, et al. Among authors: broccoli v. Nat Commun. 2017 Feb 7;8:14088. doi: 10.1038/ncomms14088. Nat Commun. 2017. PMID: 28169300 Free PMC article.
Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy.
Meneghini V, Frati G, Sala D, De Cicco S, Luciani M, Cavazzin C, Paulis M, Mentzen W, Morena F, Giannelli S, Sanvito F, Villa A, Bulfone A, Broccoli V, Martino S, Gritti A. Meneghini V, et al. Among authors: broccoli v. Stem Cells Transl Med. 2017 Feb;6(2):352-368. doi: 10.5966/sctm.2015-0414. Epub 2016 Sep 16. Stem Cells Transl Med. 2017. PMID: 28191778 Free PMC article.
CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.
Ricciardi S, Ungaro F, Hambrock M, Rademacher N, Stefanelli G, Brambilla D, Sessa A, Magagnotti C, Bachi A, Giarda E, Verpelli C, Kilstrup-Nielsen C, Sala C, Kalscheuer VM, Broccoli V. Ricciardi S, et al. Among authors: broccoli v. Nat Cell Biol. 2012 Sep;14(9):911-23. doi: 10.1038/ncb2566. Epub 2012 Aug 26. Nat Cell Biol. 2012. PMID: 22922712 Free PMC article.
153 results