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Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee.
Hamza TH, Chen H, Hill-Burns EM, Rhodes SL, Montimurro J, Kay DM, Tenesa A, Kusel VI, Sheehan P, Eaaswarkhanth M, Yearout D, Samii A, Roberts JW, Agarwal P, Bordelon Y, Park Y, Wang L, Gao J, Vance JM, Kendler KS, Bacanu SA, Scott WK, Ritz B, Nutt J, Factor SA, Zabetian CP, Payami H. Hamza TH, et al. Among authors: kendler ks. PLoS Genet. 2011 Aug;7(8):e1002237. doi: 10.1371/journal.pgen.1002237. Epub 2011 Aug 18. PLoS Genet. 2011. PMID: 21876681 Free PMC article.
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women.
Shifman S, Johannesson M, Bronstein M, Chen SX, Collier DA, Craddock NJ, Kendler KS, Li T, O'Donovan M, O'Neill FA, Owen MJ, Walsh D, Weinberger DR, Sun C, Flint J, Darvasi A. Shifman S, et al. Among authors: kendler ks. PLoS Genet. 2008 Feb;4(2):e28. doi: 10.1371/journal.pgen.0040028. PLoS Genet. 2008. PMID: 18282107 Free PMC article.
Extracting actionable information from genome scans.
Bacanu SA, Kendler KS. Bacanu SA, et al. Among authors: kendler ks. Genet Epidemiol. 2013 Jan;37(1):48-59. doi: 10.1002/gepi.21682. Epub 2012 Sep 19. Genet Epidemiol. 2013. PMID: 22996309
On schizophrenia as a "disease of humanity".
Bigdeli TB, Fanous AH, Riley BP, Reimers M; Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium; Chen X, Kendler KS, Bacanu SA. Bigdeli TB, et al. Among authors: kendler ks. Schizophr Res. 2013 Jan;143(1):223-4. doi: 10.1016/j.schres.2012.10.036. Epub 2012 Nov 20. Schizophr Res. 2013. PMID: 23182440 Free PMC article. No abstract available.
Molecular validation of the schizophrenia spectrum.
Bigdeli TB, Bacanu SA, Webb BT, Walsh D, O'Neill FA, Fanous AH, Riley BP, Kendler KS. Bigdeli TB, et al. Among authors: kendler ks. Schizophr Bull. 2014 Jan;40(1):60-5. doi: 10.1093/schbul/sbt122. Epub 2013 Aug 22. Schizophr Bull. 2014. PMID: 23970557 Free PMC article.
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
Ripke S, O'Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, Bergen SE, Collins AL, Crowley JJ, Fromer M, Kim Y, Lee SH, Magnusson PK, Sanchez N, Stahl EA, Williams S, Wray NR, Xia K, Bettella F, Borglum AD, Bulik-Sullivan BK, Cormican P, Craddock N, de Leeuw C, Durmishi N, Gill M, Golimbet V, Hamshere ML, Holmans P, Hougaard DM, Kendler KS, Lin K, Morris DW, Mors O, Mortensen PB, Neale BM, O'Neill FA, Owen MJ, Milovancevic MP, Posthuma D, Powell J, Richards AL, Riley BP, Ruderfer D, Rujescu D, Sigurdsson E, Silagadze T, Smit AB, Stefansson H, Steinberg S, Suvisaari J, Tosato S, Verhage M, Walters JT; Multicenter Genetic Studies of Schizophrenia Consortium; Levinson DF, Gejman PV, Kendler KS, Laurent C, Mowry BJ, O'Donovan MC, Owen MJ, Pulver AE, Riley BP, Schwab SG, Wildenauer DB, Dudbridge F, Holmans P, Shi J, Albus M, Alexander M, Campion D, Cohen D, Dikeos D, Duan J, Eichhammer P, Godard S, Hansen M, Lerer FB, Liang KY, Maier W, Mallet J, Nertney DA, Nestadt G, Norton N, O'Neill FA, Papadimitriou GN, Ribble R, Sanders AR, Silverman JM, Walsh D, Williams NM, Wormley B; Psychosis Endophenotypes International Consortium; Arranz MJ, Bakker S, Bender S, Bramon … See abstract for full author list ➔ Ripke S, et al. Among authors: kendler ks. Nat Genet. 2013 Oct;45(10):1150-9. doi: 10.1038/ng.2742. Epub 2013 Aug 25. Nat Genet. 2013. PMID: 23974872 Free PMC article.
The genetic overlap between schizophrenia and height.
Bacanu SA, Chen X, Kendler KS. Bacanu SA, et al. Among authors: kendler ks. Schizophr Res. 2013 Dec;151(1-3):226-8. doi: 10.1016/j.schres.2013.10.016. Epub 2013 Nov 12. Schizophr Res. 2013. PMID: 24239283 Free PMC article.
Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder.
Zhao Z, Xu J, Chen J, Kim S, Reimers M, Bacanu SA, Yu H, Liu C, Sun J, Wang Q, Jia P, Xu F, Zhang Y, Kendler KS, Peng Z, Chen X. Zhao Z, et al. Among authors: kendler ks. Mol Psychiatry. 2015 May;20(5):563-572. doi: 10.1038/mp.2014.82. Epub 2014 Aug 12. Mol Psychiatry. 2015. PMID: 25113377 Free PMC article.
JEPEGMIX: gene-level joint analysis of functional SNPs in cosmopolitan cohorts.
Lee D, Williamson VS, Bigdeli TB, Riley BP, Webb BT, Fanous AH, Kendler KS, Vladimirov VI, Bacanu SA. Lee D, et al. Among authors: kendler ks. Bioinformatics. 2016 Jan 15;32(2):295-7. doi: 10.1093/bioinformatics/btv567. Epub 2015 Oct 1. Bioinformatics. 2016. PMID: 26428293 Free PMC article.
Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.
Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O'Donovan MC, Kendler KS, Fanous AH; Schizophrenia Working Group of the Psychiatric Genomics Consortium. Bigdeli TB, et al. Among authors: kendler ks. Am J Med Genet B Neuropsychiatr Genet. 2016 Mar;171B(2):276-89. doi: 10.1002/ajmg.b.32402. Epub 2015 Dec 11. Am J Med Genet B Neuropsychiatr Genet. 2016. PMID: 26663532 Free PMC article.
1,395 results