Alt FW - Search Results

1

The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.

Gutierrez A, Kentsis A, Sanda T, Holmfeldt L, Chen SC, Zhang J, Protopopov A, Chin L, Dahlberg SE, Neuberg DS, Silverman LB, Winter SS, Hunger SP, Sallan SE, Zha S, Alt FW, Downing JR, Mullighan CG, Look AT. Gutierrez A, et al. Among authors: alt fw. Blood. 2011 Oct 13;118(15):4169-73. doi: 10.1182/blood-2010-11-318873. Epub 2011 Aug 30. Blood. 2011. PMID: 21878675 Free PMC article. Clinical Trial.

2

Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.

Sharpless NE, Ferguson DO, O'Hagan RC, Castrillon DH, Lee C, Farazi PA, Alson S, Fleming J, Morton CC, Frank K, Chin L, Alt FW, DePinho RA. Sharpless NE, et al. Among authors: alt fw. Mol Cell. 2001 Dec;8(6):1187-96. doi: 10.1016/s1097-2765(01)00425-7. Mol Cell. 2001. PMID: 11779495 Free article.

3

Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice.

Klein C, Nguyen D, Liu CH, Mizoguchi A, Bhan AK, Miki H, Takenawa T, Rosen FS, Alt FW, Mulligan RC, Snapper SB. Klein C, et al. Among authors: alt fw. Blood. 2003 Mar 15;101(6):2159-66. doi: 10.1182/blood-2002-05-1423. Epub 2002 Nov 14. Blood. 2003. PMID: 12433691 Free article.

4

Activating Notch1 mutations in mouse models of T-ALL.

O'Neil J, Calvo J, McKenna K, Krishnamoorthy V, Aster JC, Bassing CH, Alt FW, Kelliher M, Look AT. O'Neil J, et al. Among authors: alt fw. Blood. 2006 Jan 15;107(2):781-5. doi: 10.1182/blood-2005-06-2553. Epub 2005 Sep 15. Blood. 2006. PMID: 16166587 Free PMC article.

5

Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.

Zha S, Alt FW, Cheng HL, Brush JW, Li G. Zha S, et al. Among authors: alt fw. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4518-23. doi: 10.1073/pnas.0611734104. Epub 2007 Mar 7. Proc Natl Acad Sci U S A. 2007. PMID: 17360556 Free PMC article.

6

Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations.

Bassing CH, Ranganath S, Murphy M, Savic V, Gleason M, Alt FW. Bassing CH, et al. Among authors: alt fw. Blood. 2008 Feb 15;111(4):2163-9. doi: 10.1182/blood-2007-08-104760. Epub 2007 Sep 13. Blood. 2008. PMID: 17855626 Free PMC article.

7

Complementary functions of ATM and H2AX in development and suppression of genomic instability.

Zha S, Sekiguchi J, Brush JW, Bassing CH, Alt FW. Zha S, et al. Among authors: alt fw. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9302-6. doi: 10.1073/pnas.0803520105. Epub 2008 Jul 1. Proc Natl Acad Sci U S A. 2008. PMID: 18599436 Free PMC article.

8

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination.

Li G, Alt FW, Cheng HL, Brush JW, Goff PH, Murphy MM, Franco S, Zhang Y, Zha S. Li G, et al. Among authors: alt fw. Mol Cell. 2008 Sep 5;31(5):631-40. doi: 10.1016/j.molcel.2008.07.017. Mol Cell. 2008. PMID: 18775323 Free PMC article.

9

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.

Callén E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M. Callén E, et al. Among authors: alt fw. Mol Cell. 2009 May 15;34(3):285-97. doi: 10.1016/j.molcel.2009.04.025. Mol Cell. 2009. PMID: 19450527 Free PMC article.

10

Mre11: roles in DNA repair beyond homologous recombination.

Zha S, Boboila C, Alt FW. Zha S, et al. Among authors: alt fw. Nat Struct Mol Biol. 2009 Aug;16(8):798-800. doi: 10.1038/nsmb0809-798. Nat Struct Mol Biol. 2009. PMID: 19654615 No abstract available.

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