Zha S - Search Results

1

The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.

Gutierrez A, Kentsis A, Sanda T, Holmfeldt L, Chen SC, Zhang J, Protopopov A, Chin L, Dahlberg SE, Neuberg DS, Silverman LB, Winter SS, Hunger SP, Sallan SE, Zha S, Alt FW, Downing JR, Mullighan CG, Look AT. Gutierrez A, et al. Among authors: zha s. Blood. 2011 Oct 13;118(15):4169-73. doi: 10.1182/blood-2010-11-318873. Epub 2011 Aug 30. Blood. 2011. PMID: 21878675 Free PMC article. Clinical Trial.

2

Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.

Zha S, Alt FW, Cheng HL, Brush JW, Li G. Zha S, et al. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4518-23. doi: 10.1073/pnas.0611734104. Epub 2007 Mar 7. Proc Natl Acad Sci U S A. 2007. PMID: 17360556 Free PMC article.

3

Complementary functions of ATM and H2AX in development and suppression of genomic instability.

Zha S, Sekiguchi J, Brush JW, Bassing CH, Alt FW. Zha S, et al. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9302-6. doi: 10.1073/pnas.0803520105. Epub 2008 Jul 1. Proc Natl Acad Sci U S A. 2008. PMID: 18599436 Free PMC article.

4

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination.

Li G, Alt FW, Cheng HL, Brush JW, Goff PH, Murphy MM, Franco S, Zhang Y, Zha S. Li G, et al. Among authors: zha s. Mol Cell. 2008 Sep 5;31(5):631-40. doi: 10.1016/j.molcel.2008.07.017. Mol Cell. 2008. PMID: 18775323 Free PMC article.

5

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.

Callén E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M. Callén E, et al. Among authors: zha s. Mol Cell. 2009 May 15;34(3):285-97. doi: 10.1016/j.molcel.2009.04.025. Mol Cell. 2009. PMID: 19450527 Free PMC article.

6

Mre11: roles in DNA repair beyond homologous recombination.

Zha S, Boboila C, Alt FW. Zha S, et al. Nat Struct Mol Biol. 2009 Aug;16(8):798-800. doi: 10.1038/nsmb0809-798. Nat Struct Mol Biol. 2009. PMID: 19654615 No abstract available.

7

Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome.

Rucci F, Notarangelo LD, Fazeli A, Patrizi L, Hickernell T, Paganini T, Coakley KM, Detre C, Keszei M, Walter JE, Feldman L, Cheng HL, Poliani PL, Wang JH, Balter BB, Recher M, Andersson EM, Zha S, Giliani S, Terhorst C, Alt FW, Yan CT. Rucci F, et al. Among authors: zha s. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3024-9. doi: 10.1073/pnas.0914865107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133615 Free PMC article.

8

ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification.

Zha S, Bassing CH, Sanda T, Brush JW, Patel H, Goff PH, Murphy MM, Tepsuporn S, Gatti RA, Look AT, Alt FW. Zha S, et al. J Exp Med. 2010 Jul 5;207(7):1369-80. doi: 10.1084/jem.20100285. Epub 2010 Jun 21. J Exp Med. 2010. PMID: 20566716 Free PMC article.

9

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.

Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW. Zha S, et al. Nature. 2011 Jan 13;469(7329):250-4. doi: 10.1038/nature09604. Epub 2010 Dec 15. Nature. 2011. PMID: 21160472 Free PMC article.

10

Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.

Zha S, Jiang W, Fujiwara Y, Patel H, Goff PH, Brush JW, Dubois RL, Alt FW. Zha S, et al. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2028-33. doi: 10.1073/pnas.1019293108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245310 Free PMC article.

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