Loo JA - Search Results

1

Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins.

Sinha S, Lopes DH, Du Z, Pang ES, Shanmugam A, Lomakin A, Talbiersky P, Tennstaedt A, McDaniel K, Bakshi R, Kuo PY, Ehrmann M, Benedek GB, Loo JA, Klärner FG, Schrader T, Wang C, Bitan G. Sinha S, et al. Among authors: loo ja. J Am Chem Soc. 2011 Oct 26;133(42):16958-69. doi: 10.1021/ja206279b. Epub 2011 Sep 29. J Am Chem Soc. 2011. PMID: 21916458 Free PMC article.

2

Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron.

Kinzie SD, Thevis M, Ngo K, Whitelegge J, Loo JA, Abu-Omar MM. Kinzie SD, et al. Among authors: loo ja. J Am Chem Soc. 2003 Apr 23;125(16):4710-1. doi: 10.1021/ja034452y. J Am Chem Soc. 2003. PMID: 12696880

3

Top-down ESI-ECD-FT-ICR mass spectrometry localizes noncovalent protein-ligand binding sites.

Xie Y, Zhang J, Yin S, Loo JA. Xie Y, et al. Among authors: loo ja. J Am Chem Soc. 2006 Nov 15;128(45):14432-3. doi: 10.1021/ja063197p. J Am Chem Soc. 2006. PMID: 17090006

4

Amino acid position-specific contributions to amyloid beta-protein oligomerization.

Maji SK, Ogorzalek Loo RR, Inayathullah M, Spring SM, Vollers SS, Condron MM, Bitan G, Loo JA, Teplow DB. Maji SK, et al. Among authors: loo ja. J Biol Chem. 2009 Aug 28;284(35):23580-91. doi: 10.1074/jbc.M109.038133. Epub 2009 Jun 30. J Biol Chem. 2009. PMID: 19567875 Free PMC article.

5

Structural characterization of unsaturated phosphatidylcholines using traveling wave ion mobility spectrometry.

Kim HI, Kim H, Pang ES, Ryu EK, Beegle LW, Loo JA, Goddard WA, Kanik I. Kim HI, et al. Among authors: loo ja. Anal Chem. 2009 Oct 15;81(20):8289-97. doi: 10.1021/ac900672a. Anal Chem. 2009. PMID: 19764704 Free PMC article.

6

Elucidating the site of protein-ATP binding by top-down mass spectrometry.

Yin S, Loo JA. Yin S, et al. Among authors: loo ja. J Am Soc Mass Spectrom. 2010 Jun;21(6):899-907. doi: 10.1016/j.jasms.2010.01.002. Epub 2010 Jan 18. J Am Soc Mass Spectrom. 2010. PMID: 20163968 Free article.

7

Comparison of N-linked Glycoproteins in Human Whole Saliva, Parotid, Submandibular, and Sublingual Glandular Secretions Identified using Hydrazide Chemistry and Mass Spectrometry.

Ramachandran P, Boontheung P, Pang E, Yan W, Wong DT, Loo JA. Ramachandran P, et al. Among authors: loo ja. Clin Proteomics. 2008 Dec;4(3-4):80-104. doi: 10.1007/s12014-008-9005-0. Clin Proteomics. 2008. PMID: 21960768 Free PMC article.

8

Concomitant inhibition of HSP90, its mitochondrial localized homologue TRAP1 and HSP27 by green tea in pancreatic cancer HPAF-II cells.

Zhang L, Pang E, Loo RR, Rao J, Go VL, Loo JA, Lu QY. Zhang L, et al. Among authors: loo ja, loo rr. Proteomics. 2011 Dec;11(24):4638-47. doi: 10.1002/pmic.201100242. Epub 2011 Nov 23. Proteomics. 2011. PMID: 22116673 Free PMC article.

9

A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.

Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Ivanova MI, Loo JA, Klärner FG, Schrader T, Stahl M, Bitan G, Bronstein JM. Prabhudesai S, et al. Among authors: loo ja. Neurotherapeutics. 2012 Apr;9(2):464-76. doi: 10.1007/s13311-012-0105-1. Neurotherapeutics. 2012. PMID: 22373667 Free PMC article.

10

Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.

Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner FG, Schrader T, Loo JA, Bitan G, Lapidus LJ. Acharya S, et al. Among authors: loo ja. J Biol Chem. 2014 Apr 11;289(15):10727-10737. doi: 10.1074/jbc.M113.524520. Epub 2014 Feb 24. J Biol Chem. 2014. PMID: 24567327 Free PMC article.

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