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Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01.
Sinha S, Du Z, Maiti P, Klärner FG, Schrader T, Wang C, Bitan G. Sinha S, et al. ACS Chem Neurosci. 2012 Jun 20;3(6):451-8. doi: 10.1021/cn200133x. Epub 2012 Mar 7. ACS Chem Neurosci. 2012. PMID: 22860214 Free PMC article.
Many compounds have been tested as inhibitors or modulators of amyloid beta-protein (Abeta) assembly in hope that they would lead to effective, disease-modifying therapy for Alzheimer's disease (AD). These compounds typically were either designed to break apart beta-sheets …
Many compounds have been tested as inhibitors or modulators of amyloid beta-protein (Abeta) assembly in hope that they would lead to effecti …
Rational design of β-sheet ligands against Aβ42-induced toxicity.
Hochdörffer K, März-Berberich J, Nagel-Steger L, Epple M, Meyer-Zaika W, Horn AH, Sticht H, Sinha S, Bitan G, Schrader T. Hochdörffer K, et al. Among authors: sinha s. J Am Chem Soc. 2011 Mar 30;133(12):4348-58. doi: 10.1021/ja107675n. Epub 2011 Mar 7. J Am Chem Soc. 2011. PMID: 21381732
A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.
Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Ivanova MI, Loo JA, Klärner FG, Schrader T, Stahl M, Bitan G, Bronstein JM. Prabhudesai S, et al. Among authors: sinha s. Neurotherapeutics. 2012 Apr;9(2):464-76. doi: 10.1007/s13311-012-0105-1. Neurotherapeutics. 2012. PMID: 22373667 Free PMC article.
Lymphatic Interventions in Congenital Heart Disease.
Reddy SV, Sinha SP. Reddy SV, et al. Among authors: sinha sp. Interv Cardiol Clin. 2024 Jul;13(3):343-354. doi: 10.1016/j.iccl.2024.03.002. Epub 2024 Apr 20. Interv Cardiol Clin. 2024. PMID: 38839168 Review.
6,533 results