Clark A - Search Results

1

GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: implications for understanding genetic association signals at this locus.

McCulloch LJ, van de Bunt M, Braun M, Frayn KN, Clark A, Gloyn AL. McCulloch LJ, et al. Among authors: clark a. Mol Genet Metab. 2011 Dec;104(4):648-53. doi: 10.1016/j.ymgme.2011.08.026. Epub 2011 Aug 28. Mol Genet Metab. 2011. PMID: 21920790

2

Corelease and differential exit via the fusion pore of GABA, serotonin, and ATP from LDCV in rat pancreatic beta cells.

Braun M, Wendt A, Karanauskaite J, Galvanovskis J, Clark A, MacDonald PE, Rorsman P. Braun M, et al. Among authors: clark a. J Gen Physiol. 2007 Mar;129(3):221-31. doi: 10.1085/jgp.200609658. Epub 2007 Feb 12. J Gen Physiol. 2007. PMID: 17296927 Free PMC article.

3

Reversibility of metabolic and morphological changes associated with chronic exposure of pancreatic islet beta-cells to fatty acids.

Pinnick K, Neville M, Clark A, Fielding B. Pinnick K, et al. Among authors: clark a. J Cell Biochem. 2010 Mar 1;109(4):683-92. doi: 10.1002/jcb.22445. J Cell Biochem. 2010. PMID: 20069570

4

Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

Braun M, Ramracheya R, Bengtsson M, Clark A, Walker JN, Johnson PR, Rorsman P. Braun M, et al. Among authors: clark a. Diabetes. 2010 Jul;59(7):1694-701. doi: 10.2337/db09-0797. Epub 2010 Apr 22. Diabetes. 2010. PMID: 20413510 Free PMC article.

5

PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery.

Ramracheya RD, McCulloch LJ, Clark A, Wiggins D, Johannessen H, Olsen MK, Cai X, Zhao CM, Chen D, Rorsman P. Ramracheya RD, et al. Among authors: clark a. Cell Rep. 2016 May 3;15(5):944-950. doi: 10.1016/j.celrep.2016.03.091. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117413 Free PMC article.

6

Increased vimentin in human α- and β-cells in type 2 diabetes.

Roefs MM, Carlotti F, Jones K, Wills H, Hamilton A, Verschoor M, Durkin JMW, Garcia-Perez L, Brereton MF, McCulloch L, Engelse MA, Johnson PRV, Hansen BC, Docherty K, de Koning EJP, Clark A. Roefs MM, et al. Among authors: clark a. J Endocrinol. 2017 Jun;233(3):217-227. doi: 10.1530/JOE-16-0588. Epub 2017 Mar 27. J Endocrinol. 2017. PMID: 28348116

7

Is Type 2 Diabetes a Glycogen Storage Disease of Pancreatic β Cells?

Ashcroft FM, Rohm M, Clark A, Brereton MF. Ashcroft FM, et al. Among authors: clark a. Cell Metab. 2017 Jul 5;26(1):17-23. doi: 10.1016/j.cmet.2017.05.014. Cell Metab. 2017. PMID: 28683284 Free PMC article. Review.

8

Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY.

Guida C, McCulloch LJ, Godazgar M, Stephen SD, Baker C, Basco D, Dong J, Chen D, Clark A, Ramracheya RD. Guida C, et al. Among authors: clark a. Diabetes Obes Metab. 2018 Mar;20(3):571-581. doi: 10.1111/dom.13113. Epub 2017 Oct 10. Diabetes Obes Metab. 2018. PMID: 28892258 Free PMC article.

9

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.

Thomsen SK, Raimondo A, Hastoy B, Sengupta S, Dai XQ, Bautista A, Censin J, Payne AJ, Umapathysivam MM, Spigelman AF, Barrett A, Groves CJ, Beer NL, Manning Fox JE, McCarthy MI, Clark A, Mahajan A, Rorsman P, MacDonald PE, Gloyn AL. Thomsen SK, et al. Among authors: clark a. Nat Genet. 2018 Aug;50(8):1122-1131. doi: 10.1038/s41588-018-0173-1. Epub 2018 Jul 27. Nat Genet. 2018. PMID: 30054598 Free PMC article.

10

GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca²⁺ channels.

Ramracheya R, Chapman C, Chibalina M, Dou H, Miranda C, González A, Moritoh Y, Shigeto M, Zhang Q, Braun M, Clark A, Johnson PR, Rorsman P, Briant LJB. Ramracheya R, et al. Among authors: clark a. Physiol Rep. 2018 Sep;6(17):e13852. doi: 10.14814/phy2.13852. Physiol Rep. 2018. PMID: 30187652 Free PMC article.

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