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Intrinsic aerobic capacity sets a divide for aging and longevity.
Koch LG, Kemi OJ, Qi N, Leng SX, Bijma P, Gilligan LJ, Wilkinson JE, Wisløff H, Høydal MA, Rolim N, Abadir PM, van Grevenhof EM, Smith GL, Burant CF, Ellingsen O, Britton SL, Wisløff U. Koch LG, et al. Among authors: wilkinson je. Circ Res. 2011 Oct 28;109(10):1162-72. doi: 10.1161/CIRCRESAHA.111.253807. Epub 2011 Sep 15. Circ Res. 2011. PMID: 21921265 Free PMC article.
Rapamycin slows aging in mice.
Wilkinson JE, Burmeister L, Brooks SV, Chan CC, Friedline S, Harrison DE, Hejtmancik JF, Nadon N, Strong R, Wood LK, Woodward MA, Miller RA. Wilkinson JE, et al. Aging Cell. 2012 Aug;11(4):675-82. doi: 10.1111/j.1474-9726.2012.00832.x. Epub 2012 Jun 4. Aging Cell. 2012. PMID: 22587563 Free PMC article.
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.
Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, de Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ, Pletcher S, Sharp ZD, Sinclair D, Starnes JW, Wilkinson JE, Nadon NL, Strong R. Miller RA, et al. Among authors: wilkinson je. J Gerontol A Biol Sci Med Sci. 2011 Feb;66(2):191-201. doi: 10.1093/gerona/glq178. Epub 2010 Oct 25. J Gerontol A Biol Sci Med Sci. 2011. PMID: 20974732 Free PMC article.
Acarbose improves health and lifespan in aging HET3 mice.
Harrison DE, Strong R, Alavez S, Astle CM, DiGiovanni J, Fernandez E, Flurkey K, Garratt M, Gelfond JAL, Javors MA, Levi M, Lithgow GJ, Macchiarini F, Nelson JF, Sukoff Rizzo SJ, Slaga TJ, Stearns T, Wilkinson JE, Miller RA. Harrison DE, et al. Among authors: wilkinson je. Aging Cell. 2019 Apr;18(2):e12898. doi: 10.1111/acel.12898. Epub 2019 Jan 27. Aging Cell. 2019. PMID: 30688027 Free PMC article.
228 results