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Distribution of cell-free and cell-associated HIV surrogates in the colon after simulated receptive anal intercourse in men who have sex with men.
Louissaint NA, Nimmagadda S, Fuchs EJ, Bakshi RP, Cao YJ, Lee LA, Goldsmith J, Caffo BS, Du Y, King KE, Menendez FA, Torbenson MS, Hendrix CW. Louissaint NA, et al. Among authors: du y. J Acquir Immune Defic Syndr. 2012 Jan 1;59(1):10-7. doi: 10.1097/QAI.0b013e3182373b5e. J Acquir Immune Defic Syndr. 2012. PMID: 21937920 Free PMC article.
Isoosmolar enemas demonstrate preferential gastrointestinal distribution, safety, and acceptability compared with hyperosmolar and hypoosmolar enemas as a potential delivery vehicle for rectal microbicides.
Leyva FJ, Bakshi RP, Fuchs EJ, Li L, Caffo BS, Goldsmith AJ, Ventuneac A, Carballo-Diéguez A, Du Y, Leal JP, Lee LA, Torbenson MS, Hendrix CW. Leyva FJ, et al. Among authors: du y. AIDS Res Hum Retroviruses. 2013 Nov;29(11):1487-95. doi: 10.1089/aid.2013.0189. Epub 2013 Aug 24. AIDS Res Hum Retroviruses. 2013. PMID: 23885722 Free PMC article. Clinical Trial.
Simultaneous Evaluation of Safety, Acceptability, Pericoital Kinetics, and Ex Vivo Pharmacodynamics Comparing Four Rectal Microbicide Vehicle Candidates.
Leyva F, Fuchs EJ, Bakshi R, Carballo-Dieguez A, Ventuneac A, Yue C, Caffo B, Du Y, Torbenson M, Li L, Mullin G, Lee L, Rohan L, Anton PA, Hendrix CW. Leyva F, et al. Among authors: du y. AIDS Res Hum Retroviruses. 2015 Nov;31(11):1089-97. doi: 10.1089/AID.2015.0086. Epub 2015 Jul 8. AIDS Res Hum Retroviruses. 2015. PMID: 26066390 Free PMC article. Clinical Trial.
A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02).
Hiruy H, Fuchs EJ, Marzinke MA, Bakshi RP, Breakey JC, Aung WS, Manohar M, Yue C, Caffo BS, Du Y, Abebe KZ, Spiegel HM, Rohan LC, McGowan I, Hendrix CW. Hiruy H, et al. Among authors: du y. AIDS Res Hum Retroviruses. 2015 Nov;31(11):1098-108. doi: 10.1089/AID.2015.0098. Epub 2015 Aug 24. AIDS Res Hum Retroviruses. 2015. PMID: 26227279 Free PMC article. Clinical Trial.
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