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Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.
Chmielecki J, Peifer M, Viale A, Hutchinson K, Giltnane J, Socci ND, Hollis CJ, Dean RS, Yenamandra A, Jagasia M, Kim AS, Davé UP, Thomas RK, Pao W. Chmielecki J, et al. Among authors: hutchinson k. Genes Chromosomes Cancer. 2012 Jan;51(1):54-65. doi: 10.1002/gcc.20930. Epub 2011 Sep 21. Genes Chromosomes Cancer. 2012. PMID: 21938754
Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling.
Chmielecki J, Foo J, Oxnard GR, Hutchinson K, Ohashi K, Somwar R, Wang L, Amato KR, Arcila M, Sos ML, Socci ND, Viale A, de Stanchina E, Ginsberg MS, Thomas RK, Kris MG, Inoue A, Ladanyi M, Miller VA, Michor F, Pao W. Chmielecki J, et al. Among authors: hutchinson k. Sci Transl Med. 2011 Jul 6;3(90):90ra59. doi: 10.1126/scitranslmed.3002356. Sci Transl Med. 2011. PMID: 21734175 Free PMC article.
Chipping away at the lung cancer genome.
Pao W, Hutchinson KE. Pao W, et al. Nat Med. 2012 Mar 6;18(3):349-51. doi: 10.1038/nm.2697. Nat Med. 2012. PMID: 22395697 No abstract available.
Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes.
Chmielecki J, Hutchinson KE, Frampton GM, Chalmers ZR, Johnson A, Shi C, Elvin J, Ali SM, Ross JS, Basturk O, Balasubramanian S, Lipson D, Yelensky R, Pao W, Miller VA, Klimstra DS, Stephens PJ. Chmielecki J, et al. Cancer Discov. 2014 Dec;4(12):1398-405. doi: 10.1158/2159-8290.CD-14-0617. Epub 2014 Sep 29. Cancer Discov. 2014. PMID: 25266736
Melanoma BRAF fusions--response.
Hutchinson KE, Ross JS, Stephens PJ, Miller VA, Sosman JA, Pao W. Hutchinson KE, et al. Clin Cancer Res. 2014 Dec 15;20(24):6632. doi: 10.1158/1078-0432.CCR-14-1152. Clin Cancer Res. 2014. PMID: 25512636 Free PMC article. No abstract available.
312 results