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Urinary renin, but not angiotensinogen or aldosterone, reflects the renal renin-angiotensin-aldosterone system activity and the efficacy of renin-angiotensin-aldosterone system blockade in the kidney.
van den Heuvel M, Batenburg WW, Jainandunsing S, Garrelds IM, van Gool JM, Feelders RA, van den Meiracker AH, Danser AH. van den Heuvel M, et al. Among authors: van gool jm. J Hypertens. 2011 Nov;29(11):2147-55. doi: 10.1097/HJH.0b013e32834bbcbf. J Hypertens. 2011. PMID: 21941204
Cardiac Renin levels are not influenced by the amount of resident mast cells.
Krop M, van Veghel R, Garrelds IM, de Bruin RJ, van Gool JM, van den Meiracker AH, Thio M, van Daele PL, Danser AH. Krop M, et al. Among authors: van gool jm. Hypertension. 2009 Aug;54(2):315-21. doi: 10.1161/HYPERTENSIONAHA.109.133892. Epub 2009 Jun 29. Hypertension. 2009. PMID: 19564544
On the Origin of Urinary Renin: A Translational Approach.
Roksnoer LC, Heijnen BF, Nakano D, Peti-Peterdi J, Walsh SB, Garrelds IM, van Gool JM, Zietse R, Struijker-Boudier HA, Hoorn EJ, Danser AH. Roksnoer LC, et al. Among authors: van gool jm. Hypertension. 2016 May;67(5):927-33. doi: 10.1161/HYPERTENSIONAHA.115.07012. Epub 2016 Feb 29. Hypertension. 2016. PMID: 26928805 Free PMC article.
Aliskiren accumulates in Renin secretory granules and binds plasma prorenin.
Krop M, Garrelds IM, de Bruin RJ, van Gool JM, Fisher ND, Hollenberg NK, Jan Danser AH. Krop M, et al. Among authors: van gool jm. Hypertension. 2008 Dec;52(6):1076-83. doi: 10.1161/HYPERTENSIONAHA.108.123042. Epub 2008 Nov 3. Hypertension. 2008. PMID: 18981317 Clinical Trial.
Methodologic issues in the measurement of urinary renin.
Roksnoer LC, Verdonk K, Garrelds IM, van Gool JM, Zietse R, Hoorn EJ, Danser AH. Roksnoer LC, et al. Among authors: van gool jm. Clin J Am Soc Nephrol. 2014 Jul;9(7):1163-7. doi: 10.2215/CJN.12661213. Epub 2014 Apr 17. Clin J Am Soc Nephrol. 2014. PMID: 24742480 Free PMC article.
Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor-neprilysin inhibition compared with AT1 receptor blockade alone.
Roksnoer LC, van Veghel R, Clahsen-van Groningen MC, de Vries R, Garrelds IM, Bhaggoe UM, van Gool JM, Friesema EC, Leijten FP, Hoorn EJ, Danser AH, Batenburg WW. Roksnoer LC, et al. Among authors: van gool jm. Clin Sci (Lond). 2016 Jul 1;130(14):1209-20. doi: 10.1042/CS20160197. Epub 2016 Apr 19. Clin Sci (Lond). 2016. PMID: 27129187
17 results