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Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.
Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J. Beirowski B, et al. Among authors: sinclair da. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E952-61. doi: 10.1073/pnas.1104969108. Epub 2011 Sep 26. Proc Natl Acad Sci U S A. 2011. PMID: 21949390 Free PMC article.
Sirtuins: a conserved key unlocking AceCS activity.
North BJ, Sinclair DA. North BJ, et al. Among authors: sinclair da. Trends Biochem Sci. 2007 Jan;32(1):1-4. doi: 10.1016/j.tibs.2006.11.002. Epub 2006 Dec 1. Trends Biochem Sci. 2007. PMID: 17141505 Free PMC article.
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein.
Bernier M, Paul RK, Martin-Montalvo A, Scheibye-Knudsen M, Song S, He HJ, Armour SM, Hubbard BP, Bohr VA, Wang L, Zong Y, Sinclair DA, de Cabo R. Bernier M, et al. Among authors: sinclair da. J Biol Chem. 2011 Jun 3;286(22):19270-9. doi: 10.1074/jbc.M110.200311. Epub 2011 Apr 5. J Biol Chem. 2011. PMID: 21467030 Free PMC article.
The intersection between aging and cardiovascular disease.
North BJ, Sinclair DA. North BJ, et al. Among authors: sinclair da. Circ Res. 2012 Apr 13;110(8):1097-108. doi: 10.1161/CIRCRESAHA.111.246876. Circ Res. 2012. PMID: 22499900 Free PMC article. Review.
Evidence for a common mechanism of SIRT1 regulation by allosteric activators.
Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA. Hubbard BP, et al. Among authors: sinclair da. Science. 2013 Mar 8;339(6124):1216-9. doi: 10.1126/science.1231097. Science. 2013. PMID: 23471411 Free PMC article.
GLTSCR2/PICT1 links mitochondrial stress and Myc signaling.
Yoon JC, Ling AJ, Isik M, Lee DY, Steinbaugh MJ, Sack LM, Boduch AN, Blackwell TK, Sinclair DA, Elledge SJ. Yoon JC, et al. Among authors: sinclair da. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3781-6. doi: 10.1073/pnas.1400705111. Epub 2014 Feb 20. Proc Natl Acad Sci U S A. 2014. PMID: 24556985 Free PMC article.
276 results