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Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.
Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J. Beirowski B, et al. Among authors: yamamoto h. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E952-61. doi: 10.1073/pnas.1104969108. Epub 2011 Sep 26. Proc Natl Acad Sci U S A. 2011. PMID: 21949390 Free PMC article.
Sirtuin functions in health and disease.
Yamamoto H, Schoonjans K, Auwerx J. Yamamoto H, et al. Mol Endocrinol. 2007 Aug;21(8):1745-55. doi: 10.1210/me.2007-0079. Epub 2007 Apr 24. Mol Endocrinol. 2007. PMID: 17456799 Review.
SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
Rutanen J, Yaluri N, Modi S, Pihlajamäki J, Vänttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M. Rutanen J, et al. Among authors: yamamoto h. Diabetes. 2010 Apr;59(4):829-35. doi: 10.2337/db09-1191. Epub 2010 Jan 27. Diabetes. 2010. PMID: 20107110 Free PMC article.
PARP-2 regulates SIRT1 expression and whole-body energy expenditure.
Bai P, Canto C, Brunyánszki A, Huber A, Szántó M, Cen Y, Yamamoto H, Houten SM, Kiss B, Oudart H, Gergely P, Menissier-de Murcia J, Schreiber V, Sauve AA, Auwerx J. Bai P, et al. Among authors: yamamoto h. Cell Metab. 2011 Apr 6;13(4):450-460. doi: 10.1016/j.cmet.2011.03.013. Cell Metab. 2011. PMID: 21459329 Free PMC article.
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation.
Bai P, Cantó C, Oudart H, Brunyánszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, Schoonjans K, Schreiber V, Sauve AA, Menissier-de Murcia J, Auwerx J. Bai P, et al. Among authors: yamamoto h. Cell Metab. 2011 Apr 6;13(4):461-468. doi: 10.1016/j.cmet.2011.03.004. Cell Metab. 2011. PMID: 21459330 Free PMC article.
LRH-1-dependent glucose sensing determines intermediary metabolism in liver.
Oosterveer MH, Mataki C, Yamamoto H, Harach T, Moullan N, van Dijk TH, Ayuso E, Bosch F, Postic C, Groen AK, Auwerx J, Schoonjans K. Oosterveer MH, et al. Among authors: yamamoto h. J Clin Invest. 2012 Aug;122(8):2817-26. doi: 10.1172/JCI62368. Epub 2012 Jul 9. J Clin Invest. 2012. PMID: 22772466 Free PMC article.
TGR5-mediated bile acid sensing controls glucose homeostasis.
Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, Macchiarulo A, Yamamoto H, Mataki C, Pruzanski M, Pellicciari R, Auwerx J, Schoonjans K. Thomas C, et al. Among authors: yamamoto h. Cell Metab. 2009 Sep;10(3):167-77. doi: 10.1016/j.cmet.2009.08.001. Cell Metab. 2009. PMID: 19723493 Free PMC article.
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