Choi PS - Search Results

1

Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction.

Choi PS, van Riggelen J, Gentles AJ, Bachireddy P, Rakhra K, Adam SJ, Plevritis SK, Felsher DW. Choi PS, et al. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17432-7. doi: 10.1073/pnas.1107303108. Epub 2011 Oct 3. Proc Natl Acad Sci U S A. 2011. PMID: 21969595 Free PMC article.

2

Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance.

Choi PS, Li Y, Felsher DW. Choi PS, et al. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3316-24. doi: 10.1073/pnas.1406123111. Epub 2014 Jul 28. Proc Natl Acad Sci U S A. 2014. PMID: 25071175 Free PMC article.

3

Oncogene addiction: resetting the safety switch?

Li Y, Choi PS, Felsher DW. Li Y, et al. Among authors: choi ps. Oncotarget. 2014 Sep 30;5(18):7986-7. doi: 10.18632/oncotarget.2474. Oncotarget. 2014. PMID: 25275297 Free PMC article. No abstract available.

4

miR-17-92 explains MYC oncogene addiction.

Li Y, Casey SC, Choi PS, Felsher DW. Li Y, et al. Among authors: choi ps. Mol Cell Oncol. 2014 Dec 31;1(4):e970092. doi: 10.4161/23723548.2014.970092. eCollection 2014 Oct-Dec. Mol Cell Oncol. 2014. PMID: 27308380 Free PMC article.

5

Survival and death signals can predict tumor response to therapy after oncogene inactivation.

Tran PT, Bendapudi PK, Lin HJ, Choi P, Koh S, Chen J, Horng G, Hughes NP, Schwartz LH, Miller VA, Kawashima T, Kitamura T, Paik D, Felsher DW. Tran PT, et al. Sci Transl Med. 2011 Oct 5;3(103):103ra99. doi: 10.1126/scitranslmed.3002018. Sci Transl Med. 2011. PMID: 21974937 Free PMC article.

6

The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance.

van Riggelen J, Müller J, Otto T, Beuger V, Yetil A, Choi PS, Kosan C, Möröy T, Felsher DW, Eilers M. van Riggelen J, et al. Among authors: choi ps. Genes Dev. 2010 Jun 15;24(12):1281-94. doi: 10.1101/gad.585710. Genes Dev. 2010. PMID: 20551174 Free PMC article.

7

MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.

Li Y, Choi PS, Casey SC, Dill DL, Felsher DW. Li Y, et al. Among authors: choi ps. Cancer Cell. 2014 Aug 11;26(2):262-72. doi: 10.1016/j.ccr.2014.06.014. Cancer Cell. 2014. PMID: 25117713 Free PMC article.

8

Activation of Cre recombinase alone can induce complete tumor regression.

Li Y, Choi PS, Casey SC, Felsher DW. Li Y, et al. Among authors: choi ps. PLoS One. 2014 Sep 10;9(9):e107589. doi: 10.1371/journal.pone.0107589. eCollection 2014. PLoS One. 2014. PMID: 25208064 Free PMC article.

9

BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia.

Li Y, Deutzmann A, Choi PS, Fan AC, Felsher DW. Li Y, et al. Among authors: choi ps. Oncotarget. 2016 May 10;7(19):26926-34. doi: 10.18632/oncotarget.8731. Oncotarget. 2016. PMID: 27095570 Free PMC article.

10

Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.

Zhang X, Choi PS, Francis JM, Gao GF, Campbell JD, Ramachandran A, Mitsuishi Y, Ha G, Shih J, Vazquez F, Tsherniak A, Taylor AM, Zhou J, Wu Z, Berger AC, Giannakis M, Hahn WC, Cherniack AD, Meyerson M. Zhang X, et al. Among authors: choi ps. Cancer Discov. 2018 Jan;8(1):108-125. doi: 10.1158/2159-8290.CD-17-0532. Epub 2017 Sep 29. Cancer Discov. 2018. PMID: 28963353 Free PMC article.

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