Leslie RD - Search Results

1

Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis.

Rakyan VK, Beyan H, Down TA, Hawa MI, Maslau S, Aden D, Daunay A, Busato F, Mein CA, Manfras B, Dias KR, Bell CG, Tost J, Boehm BO, Beck S, Leslie RD. Rakyan VK, et al. Among authors: leslie rd. PLoS Genet. 2011 Sep;7(9):e1002300. doi: 10.1371/journal.pgen.1002300. Epub 2011 Sep 29. PLoS Genet. 2011. PMID: 21980303 Free PMC article.

2

Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes.

Alper CA, Husain Z, Larsen CE, Dubey DP, Stein R, Day C, Baker A, Beyan H, Hawa M, Ola TO, Leslie RD. Alper CA, et al. Among authors: leslie rd. J Autoimmun. 2006 Sep;27(2):89-95. doi: 10.1016/j.jaut.2006.07.007. Epub 2006 Oct 6. J Autoimmun. 2006. PMID: 17029885 Free PMC article.

3

Distinct monocyte gene-expression profiles in autoimmune diabetes.

Padmos RC, Schloot NC, Beyan H, Ruwhof C, Staal FJ, de Ridder D, Aanstoot HJ, Lam-Tse WK, de Wit H, de Herder C, Drexhage RC, Menart B, Leslie RD, Drexhage HA; LADA Consortium. Padmos RC, et al. Among authors: leslie rd. Diabetes. 2008 Oct;57(10):2768-73. doi: 10.2337/db08-0496. Epub 2008 Jul 3. Diabetes. 2008. PMID: 18599519 Free PMC article.

4

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains.

Rakyan VK, Down TA, Maslau S, Andrew T, Yang TP, Beyan H, Whittaker P, McCann OT, Finer S, Valdes AM, Leslie RD, Deloukas P, Spector TD. Rakyan VK, et al. Among authors: leslie rd. Genome Res. 2010 Apr;20(4):434-9. doi: 10.1101/gr.103101.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219945 Free PMC article.

5

Metabolomics makes a mark: early changes associated with autoimmune diabetes.

Leslie RD, Beyan H. Leslie RD, et al. Diabetes. 2011 Nov;60(11):2688-90. doi: 10.2337/db11-1177. Diabetes. 2011. PMID: 22025776 Free PMC article. No abstract available.

6

Glycotoxin and autoantibodies are additive environmentally determined predictors of type 1 diabetes: a twin and population study.

Beyan H, Riese H, Hawa MI, Beretta G, Davidson HW, Hutton JC, Burger H, Schlosser M, Snieder H, Boehm BO, Leslie RD. Beyan H, et al. Among authors: leslie rd. Diabetes. 2012 May;61(5):1192-8. doi: 10.2337/db11-0971. Epub 2012 Mar 6. Diabetes. 2012. PMID: 22396204 Free PMC article.

7

Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans.

Beyan H, Down TA, Ramagopalan SV, Uvebrant K, Nilsson A, Holland ML, Gemma C, Giovannoni G, Boehm BO, Ebers GC, Lernmark Å, Cilio CM, Leslie RD, Rakyan VK. Beyan H, et al. Among authors: leslie rd. Genome Res. 2012 Nov;22(11):2138-45. doi: 10.1101/gr.134304.111. Epub 2012 Aug 23. Genome Res. 2012. PMID: 22919074 Free PMC article.

8

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies.

Lowe R, Gemma C, Beyan H, Hawa MI, Bazeos A, Leslie RD, Montpetit A, Rakyan VK, Ramagopalan SV. Lowe R, et al. Among authors: leslie rd. Epigenetics. 2013 Apr;8(4):445-54. doi: 10.4161/epi.24362. Epub 2013 Mar 28. Epigenetics. 2013. PMID: 23538714 Free PMC article.

9

Inactive or moderately active human promoters are enriched for inter-individual epialleles.

Gemma C, Ramagopalan SV, Down TA, Beyan H, Hawa MI, Holland ML, Hurd PJ, Giovannoni G, Leslie RD, Ebers GC, Rakyan VK. Gemma C, et al. Among authors: leslie rd. Genome Biol. 2013 May 25;14(5):R43. doi: 10.1186/gb-2013-14-5-r43. Genome Biol. 2013. PMID: 23706135 Free PMC article.

10

Methylation Analysis in Distinct Immune Cell Subsets in Type 1 Diabetes.

Dang MN, Bradford CM, Pozzilli P, Leslie RD. Dang MN, et al. Among authors: leslie rd. Methods Mol Biol. 2016;1433:143-51. doi: 10.1007/7651_2015_286. Methods Mol Biol. 2016. PMID: 26791360

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