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Apaf1 plays a pro-survival role by regulating centrosome morphology and function.
J Cell Sci. 2011 Oct 15;124(Pt 20):3450-63. doi: 10.1242/jcs.086298. Epub 2011 Oct 7.
J Cell Sci. 2011.
PMID: 21984814
Free article.
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation.
Pesaresi MG, Amori I, Giorgi C, Ferri A, Fiorenzo P, Gabanella F, Salvatore AM, Giorgio M, Pelicci PG, Pinton P, Carrì MT, Cozzolino M.
Pesaresi MG, et al.
Hum Mol Genet. 2011 Nov 1;20(21):4196-208. doi: 10.1093/hmg/ddr347. Epub 2011 Aug 9.
Hum Mol Genet. 2011.
PMID: 21828072
Free article.
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Oligomerization of mutant SOD1 in mitochondria of motoneuronal cells drives mitochondrial damage and cell toxicity.
Cozzolino M, Pesaresi MG, Amori I, Crosio C, Ferri A, Nencini M, Carrì MT.
Cozzolino M, et al. Among authors: pesaresi mg.
Antioxid Redox Signal. 2009 Jul;11(7):1547-58. doi: 10.1089/ars.2009.2545.
Antioxid Redox Signal. 2009.
PMID: 19344252
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Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention.
Cozzolino M, Pesaresi MG, Gerbino V, Grosskreutz J, Carrì MT.
Cozzolino M, et al. Among authors: pesaresi mg.
Antioxid Redox Signal. 2012 Nov 1;17(9):1277-330. doi: 10.1089/ars.2011.4328. Epub 2012 Apr 30.
Antioxid Redox Signal. 2012.
PMID: 22413952
Review.
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Cysteine 111 affects aggregation and cytotoxicity of mutant Cu,Zn-superoxide dismutase associated with familial amyotrophic lateral sclerosis.
Cozzolino M, Amori I, Pesaresi MG, Ferri A, Nencini M, Carrì MT.
Cozzolino M, et al. Among authors: pesaresi mg.
J Biol Chem. 2008 Jan 11;283(2):866-74. doi: 10.1074/jbc.M705657200. Epub 2007 Nov 15.
J Biol Chem. 2008.
PMID: 18006498
Free PMC article.
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Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity.
Ferri A, Fiorenzo P, Nencini M, Cozzolino M, Pesaresi MG, Valle C, Sepe S, Moreno S, Carrì MT.
Ferri A, et al. Among authors: pesaresi mg.
Hum Mol Genet. 2010 Nov 15;19(22):4529-42. doi: 10.1093/hmg/ddq383. Epub 2010 Sep 9.
Hum Mol Genet. 2010.
PMID: 20829229
Free PMC article.
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The NADPH oxidase pathway is dysregulated by the P2X7 receptor in the SOD1-G93A microglia model of amyotrophic lateral sclerosis.
Apolloni S, Parisi C, Pesaresi MG, Rossi S, Carrì MT, Cozzolino M, Volonté C, D'Ambrosi N.
Apolloni S, et al. Among authors: pesaresi mg.
J Immunol. 2013 May 15;190(10):5187-95. doi: 10.4049/jimmunol.1203262. Epub 2013 Apr 15.
J Immunol. 2013.
PMID: 23589615
Free article.
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Mutant SOD1 and mitochondrial damage alter expression and splicing of genes controlling neuritogenesis in models of neurodegeneration.
Lenzken SC, Romeo V, Zolezzi F, Cordero F, Lamorte G, Bonanno D, Biancolini D, Cozzolino M, Pesaresi MG, Maracchioni A, Sanges R, Achsel T, Carrì MT, Calogero RA, Barabino SM.
Lenzken SC, et al. Among authors: pesaresi mg.
Hum Mutat. 2011 Feb;32(2):168-82. doi: 10.1002/humu.21394. Epub 2011 Jan 25.
Hum Mutat. 2011.
PMID: 21120952
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