Musacchio A - Search Results

1

Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen.

Kwiatkowski N, Deng X, Wang J, Tan L, Villa F, Santaguida S, Huang HC, Mitchison T, Musacchio A, Gray N. Kwiatkowski N, et al. Among authors: musacchio a. ACS Chem Biol. 2012 Jan 20;7(1):185-96. doi: 10.1021/cb200305u. Epub 2011 Oct 21. ACS Chem Biol. 2012. PMID: 21992004 Free PMC article.

2

Defining Cdk5 ligand chemical space with small molecule inhibitors of tau phosphorylation.

Ahn JS, Radhakrishnan ML, Mapelli M, Choi S, Tidor B, Cuny GD, Musacchio A, Yeh LA, Kosik KS. Ahn JS, et al. Among authors: musacchio a. Chem Biol. 2005 Jul;12(7):811-23. doi: 10.1016/j.chembiol.2005.05.011. Chem Biol. 2005. PMID: 16039528

3

The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint.

Mapelli M, Massimiliano L, Santaguida S, Musacchio A. Mapelli M, et al. Among authors: musacchio a. Cell. 2007 Nov 16;131(4):730-43. doi: 10.1016/j.cell.2007.08.049. Cell. 2007. PMID: 18022367 Free article.

4

Discovery of selective aminothiazole aurora kinase inhibitors.

Andersen CB, Wan Y, Chang JW, Riggs B, Lee C, Liu Y, Sessa F, Villa F, Kwiatkowski N, Suzuki M, Nallan L, Heald R, Musacchio A, Gray NS. Andersen CB, et al. Among authors: musacchio a. ACS Chem Biol. 2008 Mar 20;3(3):180-92. doi: 10.1021/cb700200w. Epub 2008 Feb 29. ACS Chem Biol. 2008. PMID: 18307303

5

Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells.

D'Alise AM, Amabile G, Iovino M, Di Giorgio FP, Bartiromo M, Sessa F, Villa F, Musacchio A, Cortese R. D'Alise AM, et al. Among authors: musacchio a. Mol Cancer Ther. 2008 May;7(5):1140-9. doi: 10.1158/1535-7163.MCT-07-2051. Mol Cancer Ther. 2008. PMID: 18483302

6

Molecular basis of drug resistance in aurora kinases.

Girdler F, Sessa F, Patercoli S, Villa F, Musacchio A, Taylor S. Girdler F, et al. Among authors: musacchio a. Chem Biol. 2008 Jun;15(6):552-62. doi: 10.1016/j.chembiol.2008.04.013. Chem Biol. 2008. PMID: 18559266

7

The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts.

Amabile G, D'Alise AM, Iovino M, Jones P, Santaguida S, Musacchio A, Taylor S, Cortese R. Amabile G, et al. Among authors: musacchio a. Cell Death Differ. 2009 Feb;16(2):321-30. doi: 10.1038/cdd.2008.156. Epub 2008 Oct 31. Cell Death Differ. 2009. PMID: 18974773 Free article.

8

A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor.

DeMoe JH, Santaguida S, Daum JR, Musacchio A, Gorbsky GJ. DeMoe JH, et al. Among authors: musacchio a. Cancer Res. 2009 Feb 15;69(4):1509-16. doi: 10.1158/0008-5472.CAN-08-3133. Epub 2009 Feb 3. Cancer Res. 2009. PMID: 19190331 Free PMC article.

9

The life and miracles of kinetochores.

Santaguida S, Musacchio A. Santaguida S, et al. Among authors: musacchio a. EMBO J. 2009 Sep 2;28(17):2511-31. doi: 10.1038/emboj.2009.173. Epub 2009 Jul 23. EMBO J. 2009. PMID: 19629042 Free PMC article. Review.

10

Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization.

Villa F, Capasso P, Tortorici M, Forneris F, de Marco A, Mattevi A, Musacchio A. Villa F, et al. Among authors: musacchio a. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20204-9. doi: 10.1073/pnas.0908485106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918049 Free PMC article.

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