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Estimation of rearrangement phylogeny for cancer genomes.
Greenman CD, Pleasance ED, Newman S, Yang F, Fu B, Nik-Zainal S, Jones D, Lau KW, Carter N, Edwards PA, Futreal PA, Stratton MR, Campbell PJ. Greenman CD, et al. Among authors: edwards pa. Genome Res. 2012 Feb;22(2):346-61. doi: 10.1101/gr.118414.110. Epub 2011 Oct 12. Genome Res. 2012. PMID: 21994251 Free PMC article.
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution.
Bignell GR, Santarius T, Pole JC, Butler AP, Perry J, Pleasance E, Greenman C, Menzies A, Taylor S, Edkins S, Campbell P, Quail M, Plumb B, Matthews L, McLay K, Edwards PA, Rogers J, Wooster R, Futreal PA, Stratton MR. Bignell GR, et al. Among authors: edwards pa. Genome Res. 2007 Sep;17(9):1296-303. doi: 10.1101/gr.6522707. Epub 2007 Aug 3. Genome Res. 2007. PMID: 17675364 Free PMC article.
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing.
Campbell PJ, Stephens PJ, Pleasance ED, O'Meara S, Li H, Santarius T, Stebbings LA, Leroy C, Edkins S, Hardy C, Teague JW, Menzies A, Goodhead I, Turner DJ, Clee CM, Quail MA, Cox A, Brown C, Durbin R, Hurles ME, Edwards PA, Bignell GR, Stratton MR, Futreal PA. Campbell PJ, et al. Among authors: edwards pa. Nat Genet. 2008 Jun;40(6):722-9. doi: 10.1038/ng.128. Epub 2008 Apr 27. Nat Genet. 2008. PMID: 18438408 Free PMC article.
Single-molecule analysis of genome rearrangements in cancer.
Pole JC, McCaughan F, Newman S, Howarth KD, Dear PH, Edwards PA. Pole JC, et al. Among authors: edwards pa. Nucleic Acids Res. 2011 Jul;39(13):e85. doi: 10.1093/nar/gkr227. Epub 2011 Apr 27. Nucleic Acids Res. 2011. PMID: 21525129 Free PMC article.
A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P. A. W. Edwards, P. D. Smith, S. J. Cook.
Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ. Little AS, et al. Among authors: edwards pa. Sci Signal. 2011;4(170):er2. doi: 10.1126/scisignal.4170er2. Sci Signal. 2011. PMID: 21674991
443 results