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Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models.
Härmä V, Knuuttila M, Virtanen J, Mirtti T, Kohonen P, Kovanen P, Happonen A, Kaewphan S, Ahonen I, Kallioniemi O, Grafström R, Lötjönen J, Nees M. Härmä V, et al. Among authors: virtanen j. Oncogene. 2012 Apr 19;31(16):2075-89. doi: 10.1038/onc.2011.396. Epub 2011 Sep 26. Oncogene. 2012. PMID: 21996742 Free PMC article.
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion.
Björkman M, Östling P, Härmä V, Virtanen J, Mpindi JP, Rantala J, Mirtti T, Vesterinen T, Lundin M, Sankila A, Rannikko A, Kaivanto E, Kohonen P, Kallioniemi O, Nees M. Björkman M, et al. Among authors: virtanen j. Oncogene. 2012 Jul 19;31(29):3444-56. doi: 10.1038/onc.2011.512. Epub 2011 Nov 28. Oncogene. 2012. PMID: 22120715
Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.
Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, Orešič M, Kallioniemi O, Iljin K. Vainio P, et al. Among authors: virtanen j. Oncotarget. 2011 Dec;2(12):1176-90. doi: 10.18632/oncotarget.397. Oncotarget. 2011. PMID: 22202492 Free PMC article.
Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention.
Åkerfelt M, Bayramoglu N, Robinson S, Toriseva M, Schukov HP, Härmä V, Virtanen J, Sormunen R, Kaakinen M, Kannala J, Eklund L, Heikkilä J, Nees M. Åkerfelt M, et al. Among authors: virtanen j. Oncotarget. 2015 Oct 6;6(30):30035-56. doi: 10.18632/oncotarget.5046. Oncotarget. 2015. PMID: 26375443 Free PMC article.
Marine Microalgae: Promising Source for New Bioactive Compounds.
de Vera CR, Díaz Crespín G, Hernández Daranas A, Montalvão Looga S, Lillsunde KE, Tammela P, Perälä M, Hongisto V, Virtanen J, Rischer H, Muller CD, Norte M, Fernández JJ, Souto ML. de Vera CR, et al. Among authors: virtanen j. Mar Drugs. 2018 Sep 6;16(9):317. doi: 10.3390/md16090317. Mar Drugs. 2018. PMID: 30200664 Free PMC article.
521 results