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The impact of aging on memory T cell phenotype and function in the human bone marrow.
Herndler-Brandstetter D, Landgraf K, Tzankov A, Jenewein B, Brunauer R, Laschober GT, Parson W, Kloss F, Gassner R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. J Leukoc Biol. 2012 Feb;91(2):197-205. doi: 10.1189/jlb.0611299. Epub 2011 Oct 19. J Leukoc Biol. 2012. PMID: 22013229
Post-thymic regulation of CD5 levels in human memory T cells is inversely associated with the strength of responsiveness to interleukin-15.
Herndler-Brandstetter D, Brunner S, Weiskopf D, van Rijn R, Landgraf K, Dejaco C, Duftner C, Schirmer M, Kloss F, Gassner R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. Hum Immunol. 2011 Aug;72(8):627-31. doi: 10.1016/j.humimm.2011.03.028. Epub 2011 Apr 15. Hum Immunol. 2011. PMID: 21539877 Free PMC article.
Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons.
Almanzar G, Schwaiger S, Jenewein B, Keller M, Herndler-Brandstetter D, Würzner R, Schönitzer D, Grubeck-Loebenstein B. Almanzar G, et al. J Virol. 2005 Mar;79(6):3675-83. doi: 10.1128/JVI.79.6.3675-3683.2005. J Virol. 2005. PMID: 15731261 Free PMC article.
CD25-expressing CD8+ T cells are potent memory cells in old age.
Herndler-Brandstetter D, Schwaiger S, Veel E, Fehrer C, Cioca DP, Almanzar G, Keller M, Pfister G, Parson W, Würzner R, Schönitzer D, Henson SM, Aspinall R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. J Immunol. 2005 Aug 1;175(3):1566-74. doi: 10.4049/jimmunol.175.3.1566. J Immunol. 2005. PMID: 16034095
238 results