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Selective inhibition of p300 HAT blocks cell cycle progression, induces cellular senescence, and inhibits the DNA damage response in melanoma cells.
Yan G, Eller MS, Elm C, Larocca CA, Ryu B, Panova IP, Dancy BM, Bowers EM, Meyers D, Lareau L, Cole PA, Taverna SD, Alani RM. Yan G, et al. Among authors: taverna sd. J Invest Dermatol. 2013 Oct;133(10):2444-2452. doi: 10.1038/jid.2013.187. Epub 2013 Apr 18. J Invest Dermatol. 2013. PMID: 23698071 Free PMC article.
A selective phenelzine analogue inhibitor of histone demethylase LSD1.
Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA Jr, Taverna SD, Qian J, Tackett AJ, Ratan RR, McDonald OG, Feinberg AP, Cole PA. Prusevich P, et al. Among authors: taverna sd. ACS Chem Biol. 2014 Jun 20;9(6):1284-93. doi: 10.1021/cb500018s. Epub 2014 Apr 7. ACS Chem Biol. 2014. PMID: 24707965 Free PMC article.
A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.
Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BC, Wade H, Tackett AJ, Strahl BD, Taverna SD. Gilbert TM, et al. Among authors: taverna sd. Mol Cell Proteomics. 2014 Nov;13(11):2883-95. doi: 10.1074/mcp.M114.038224. Epub 2014 Aug 6. Mol Cell Proteomics. 2014. PMID: 25104842 Free PMC article.
The bromodomain of Gcn5 regulates site specificity of lysine acetylation on histone H3.
Cieniewicz AM, Moreland L, Ringel AE, Mackintosh SG, Raman A, Gilbert TM, Wolberger C, Tackett AJ, Taverna SD. Cieniewicz AM, et al. Among authors: taverna sd. Mol Cell Proteomics. 2014 Nov;13(11):2896-910. doi: 10.1074/mcp.M114.038174. Epub 2014 Aug 8. Mol Cell Proteomics. 2014. PMID: 25106422 Free PMC article.
Azalysine analogues as probes for protein lysine deacetylation and demethylation.
Dancy BC, Ming SA, Papazyan R, Jelinek CA, Majumdar A, Sun Y, Dancy BM, Drury WJ 3rd, Cotter RJ, Taverna SD, Cole PA. Dancy BC, et al. Among authors: taverna sd. J Am Chem Soc. 2012 Mar 21;134(11):5138-48. doi: 10.1021/ja209574z. Epub 2012 Mar 12. J Am Chem Soc. 2012. PMID: 22352831 Free PMC article.
43 results