Holness MJ - Search Results

1

Endogenous epoxygenases are modulators of monocyte/macrophage activity.

Bystrom J, Wray JA, Sugden MC, Holness MJ, Swales KE, Warner TD, Edin ML, Zeldin DC, Gilroy DW, Bishop-Bailey D. Bystrom J, et al. Among authors: holness mj. PLoS One. 2011;6(10):e26591. doi: 10.1371/journal.pone.0026591. Epub 2011 Oct 19. PLoS One. 2011. PMID: 22028915 Free PMC article.

2

The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo.

Wray JA, Sugden MC, Zeldin DC, Greenwood GK, Samsuddin S, Miller-Degraff L, Bradbury JA, Holness MJ, Warner TD, Bishop-Bailey D. Wray JA, et al. Among authors: holness mj. PLoS One. 2009 Oct 12;4(10):e7421. doi: 10.1371/journal.pone.0007421. PLoS One. 2009. PMID: 19823578 Free PMC article.

3

Epigenetic regulation of metabolism in children born small for gestational age.

Holness MJ, Sugden MC. Holness MJ, et al. Curr Opin Clin Nutr Metab Care. 2006 Jul;9(4):482-8. doi: 10.1097/01.mco.0000232912.69236.e0. Curr Opin Clin Nutr Metab Care. 2006. PMID: 16778581 Review.

4

Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases.

Sugden MC, Holness MJ. Sugden MC, et al. Among authors: holness mj. Arch Physiol Biochem. 2006 Jul;112(3):139-49. doi: 10.1080/13813450600935263. Arch Physiol Biochem. 2006. PMID: 17132539 Review.

5

Acute and long-term nutrient-led modifications of gene expression: potential role of SIRT1 as a central co-ordinator of short and longer-term programming of tissue function.

Holness MJ, Caton PW, Sugden MC. Holness MJ, et al. Nutrition. 2010 May;26(5):491-501. doi: 10.1016/j.nut.2009.09.012. Epub 2010 Jan 25. Nutrition. 2010. PMID: 20097539 Review.

6

PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.

Caton PW, Holness MJ, Bishop-Bailey D, Sugden MC. Caton PW, et al. Among authors: holness mj. Biochem J. 2011 Aug 1;437(3):521-30. doi: 10.1042/BJ20110702. Biochem J. 2011. PMID: 21609322

7

Interactive regulation of the pyruvate dehydrogenase complex and the carnitine palmitoyltransferase system.

Sugden MC, Holness MJ. Sugden MC, et al. Among authors: holness mj. FASEB J. 1994 Jan;8(1):54-61. doi: 10.1096/fasebj.8.1.8299890. FASEB J. 1994. PMID: 8299890 Review.

8

Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism.

Holness MJ, Smith ND, Bulmer K, Hopkins T, Gibbons GF, Sugden MC. Holness MJ, et al. Biochem J. 2002 Jun 15;364(Pt 3):687-94. doi: 10.1042/BJ20011841. Biochem J. 2002. PMID: 12049632 Free PMC article.

9

Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha).

Holness MJ, Bulmer K, Gibbons GF, Sugden MC. Holness MJ, et al. Biochem J. 2002 Sep 15;366(Pt 3):839-46. doi: 10.1042/BJ20020754. Biochem J. 2002. PMID: 12099888 Free PMC article.

10

Peroxisome proliferator-activated receptor-alpha activation during pregnancy attenuates glucose-stimulated insulin hypersecretion in vivo by increasing insulin sensitivity, without impairing pregnancy-induced increases in beta-cell glucose sensing and responsiveness.

Sugden MC, Greenwood GK, Smith ND, Holness MJ. Sugden MC, et al. Among authors: holness mj. Endocrinology. 2003 Jan;144(1):146-53. doi: 10.1210/en.2002-220811. Endocrinology. 2003. PMID: 12488340

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