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Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase.
Cazier JB, Kaisaki PJ, Argoud K, Blaise BJ, Veselkov K, Ebbels TM, Tsang T, Wang Y, Bihoreau MT, Mitchell SC, Holmes EC, Lindon JC, Scott J, Nicholson JK, Dumas ME, Gauguier D. Cazier JB, et al. Among authors: gauguier d. J Proteome Res. 2012 Feb 3;11(2):631-42. doi: 10.1021/pr200566t. Epub 2011 Nov 28. J Proteome Res. 2012. PMID: 22029865
Characterization of a major modifier locus for polycystic kidney disease (Modpkdr1) in the Han:SPRD(cy/+) rat in a region conserved with a mouse modifier locus for Alport syndrome.
Bihoreau MT, Megel N, Brown JH, Kränzlin B, Crombez L, Tychinskaya Y, Broxholme J, Kratz S, Bergmann V, Hoffman S, Gauguier D, Gretz N. Bihoreau MT, et al. Among authors: gauguier d. Hum Mol Genet. 2002 Sep 1;11(18):2165-73. doi: 10.1093/hmg/11.18.2165. Hum Mol Genet. 2002. PMID: 12189169
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.
Solberg LC, Valdar W, Gauguier D, Nunez G, Taylor A, Burnett S, Arboledas-Hita C, Hernandez-Pliego P, Davidson S, Burns P, Bhattacharya S, Hough T, Higgs D, Klenerman P, Cookson WO, Zhang Y, Deacon RM, Rawlins JN, Mott R, Flint J. Solberg LC, et al. Among authors: gauguier d. Mamm Genome. 2006 Feb;17(2):129-46. doi: 10.1007/s00335-005-0112-1. Epub 2006 Feb 6. Mamm Genome. 2006. PMID: 16465593
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice.
Dumas ME, Barton RH, Toye A, Cloarec O, Blancher C, Rothwell A, Fearnside J, Tatoud R, Blanc V, Lindon JC, Mitchell SC, Holmes E, McCarthy MI, Scott J, Gauguier D, Nicholson JK. Dumas ME, et al. Among authors: gauguier d. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12511-6. doi: 10.1073/pnas.0601056103. Epub 2006 Aug 8. Proc Natl Acad Sci U S A. 2006. PMID: 16895997 Free PMC article.
158 results