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Long-term safety and tolerability of the oral direct renin inhibitor aliskiren with optional add-on hydrochlorothiazide in patients with hypertension: a randomized, open-label, parallel-group, multicentre, dose-escalation study with an extension phase.
Sica D, Gradman AH, Lederballe O, Kolloch RE, Zhang J, Keefe DL. Sica D, et al. Among authors: keefe dl. Clin Drug Investig. 2011 Dec 1;31(12):825-37. doi: 10.1007/BF03256921. Clin Drug Investig. 2011. PMID: 22035463 Clinical Trial.
Evaluation of the dose--response relationship of aliskiren, a direct renin inhibitor, in an 8-week, multicenter, randomized, double-blind, parallel-group, placebo-controlled study in adult patients with stage 1 or 2 essential hypertension.
Puig JG, Schunkert H, Taylor AA, Boye S, Jin J, Keefe DL. Puig JG, et al. Among authors: keefe dl. Clin Ther. 2009 Dec;31(12):2839-50. doi: 10.1016/j.clinthera.2009.12.006. Clin Ther. 2009. PMID: 20110023 Clinical Trial.
274 results