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The postmenopausal hormone replacement therapy-related breast cancer risk is decreased in women carrying the CYP2C19*17 variant.
Justenhoven C, Obazee O, Winter S, Couch FJ, Olson JE, Hall P, Hannelius U, Li J, Humphreys K, Severi G, Giles G, Southey M, Baglietto L, Fasching PA, Beckmann MW, Ekici AB, Hamann U, Baisch C, Harth V, Rabstein S, Lotz A, Pesch B, Brüning T, Ko YD, Brauch H. Justenhoven C, et al. Among authors: winter s. Breast Cancer Res Treat. 2012 Jan;131(1):347-50. doi: 10.1007/s10549-011-1827-1. Epub 2011 Oct 26. Breast Cancer Res Treat. 2012. PMID: 22037784 No abstract available.
CYP2C19*17 is associated with decreased breast cancer risk.
Justenhoven C, Hamann U, Pierl CB, Baisch C, Harth V, Rabstein S, Spickenheuer A, Pesch B, Brüning T, Winter S, Ko YD, Brauch H. Justenhoven C, et al. Among authors: winter s. Breast Cancer Res Treat. 2009 May;115(2):391-6. doi: 10.1007/s10549-008-0076-4. Epub 2008 Jun 3. Breast Cancer Res Treat. 2009. PMID: 18521743
Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen.
Schroth W, Goetz MP, Hamann U, Fasching PA, Schmidt M, Winter S, Fritz P, Simon W, Suman VJ, Ames MM, Safgren SL, Kuffel MJ, Ulmer HU, Boländer J, Strick R, Beckmann MW, Koelbl H, Weinshilboum RM, Ingle JN, Eichelbaum M, Schwab M, Brauch H. Schroth W, et al. Among authors: winter s. JAMA. 2009 Oct 7;302(13):1429-36. doi: 10.1001/jama.2009.1420. JAMA. 2009. PMID: 19809024 Free PMC article.
Polymorphisms of the nuclear receptor pregnane X receptor and organic anion transporter polypeptides 1A2, 1B1, 1B3, and 2B1 are not associated with breast cancer risk.
Justenhoven C, Schaeffeler E, Winter S, Baisch C, Hamann U, Harth V, Rabstein S, Spickenheuer A, Pesch B, Brüning T, Ko YD, Schwab M, Brauch H. Justenhoven C, et al. Among authors: winter s. Breast Cancer Res Treat. 2011 Jan;125(2):563-9. doi: 10.1007/s10549-010-1046-1. Epub 2010 Jul 16. Breast Cancer Res Treat. 2011. PMID: 20635135
Tamoxifen use in postmenopausal breast cancer: CYP2D6 matters.
Brauch H, Schroth W, Goetz MP, Mürdter TE, Winter S, Ingle JN, Schwab M, Eichelbaum M. Brauch H, et al. Among authors: winter s. J Clin Oncol. 2013 Jan 10;31(2):176-80. doi: 10.1200/JCO.2012.44.6625. Epub 2012 Oct 22. J Clin Oncol. 2013. PMID: 23091108 Free PMC article. No abstract available.
1,774 results