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Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.
Bioorg Med Chem Lett. 2011 Dec 15;21(24):7416-20. doi: 10.1016/j.bmcl.2011.10.010. Epub 2011 Oct 12.
Bioorg Med Chem Lett. 2011.
PMID: 22041057
Synthesis of a tetrahydronaphthyridine spiropyrimidinetrione DNA gyrase inhibiting antibacterial agent--differential substitution at all five carbon atoms of pyridine.
Basarab GS, Galullo V, DeGrace N, Hauck S, Joubran C, Wesolowski SS.
Basarab GS, et al. Among authors: degrace n.
Org Lett. 2014 Dec 19;16(24):6456-9. doi: 10.1021/ol503256h. Epub 2014 Dec 2.
Org Lett. 2014.
PMID: 25458849
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Discovery of novel Jak2-Stat pathway inhibitors with extended residence time on target.
Guan H, Lamb ML, Peng B, Huang S, Degrace N, Read J, Hussain S, Wu J, Rivard C, Alimzhanov M, Bebernitz G, Bell K, Ye M, Zinda M, Ioannidis S.
Guan H, et al. Among authors: degrace n.
Bioorg Med Chem Lett. 2013 May 15;23(10):3105-10. doi: 10.1016/j.bmcl.2013.02.111. Epub 2013 Mar 7.
Bioorg Med Chem Lett. 2013.
PMID: 23562594
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Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors.
Yang B, Vasbinder MM, Hird AW, Su Q, Wang H, Yu Y, Toader D, Lyne PD, Read JA, Breed J, Ioannidis S, Deng C, Grondine M, DeGrace N, Whitston D, Brassil P, Janetka JW.
Yang B, et al. Among authors: degrace n.
J Med Chem. 2018 Feb 8;61(3):1061-1073. doi: 10.1021/acs.jmedchem.7b01490. Epub 2018 Jan 19.
J Med Chem. 2018.
PMID: 29301085
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Discovery and Characterization of New Hydroxamate Siderophores, Baumannoferrin A and B, produced by Acinetobacter baumannii.
Penwell WF, DeGrace N, Tentarelli S, Gauthier L, Gilbert CM, Arivett BA, Miller AA, Durand-Reville TF, Joubran C, Actis LA.
Penwell WF, et al. Among authors: degrace n.
Chembiochem. 2015 Sep 7;16(13):1896-1904. doi: 10.1002/cbic.201500147. Epub 2015 Jul 27.
Chembiochem. 2015.
PMID: 26235845
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Synthesis of Substituted Pentafluorosulfanylpyrazoles Under Flow Conditions.
Paquin P, DeGrâce N, Bélanger-Chabot G, Paquin JF.
Paquin P, et al. Among authors: degrace n.
J Org Chem. 2024 Mar 1;89(5):3552-3562. doi: 10.1021/acs.joc.3c02295. Epub 2024 Feb 8.
J Org Chem. 2024.
PMID: 38329971
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