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Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
Nat Genet. 2011 Nov 6;43(12):1256-61. doi: 10.1038/ng.1004.
Nat Genet. 2011.
PMID: 22057234
Free PMC article.
R132C IDH1 mutations are found in spindle cell hemangiomas and not in other vascular tumors or malformations.
Kurek KC, Pansuriya TC, van Ruler MA, van den Akker B, Luks VL, Verbeke SL, Kozakewich HP, Sciot R, Lev D, Lazar AJ, Fletcher CD, Bovée JV.
Kurek KC, et al. Among authors: van ruler ma.
Am J Pathol. 2013 May;182(5):1494-500. doi: 10.1016/j.ajpath.2013.01.012. Epub 2013 Feb 26.
Am J Pathol. 2013.
PMID: 23485734
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Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone.
van Oosterwijk JG, de Jong D, van Ruler MA, Hogendoorn PC, Dijkstra PD, van Rijswijk CS, Machado I, Llombart-Bosch A, Szuhai K, Bovée JV.
van Oosterwijk JG, et al. Among authors: van ruler ma.
BMC Cancer. 2012 Aug 28;12:375. doi: 10.1186/1471-2407-12-375.
BMC Cancer. 2012.
PMID: 22928481
Free PMC article.
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Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells.
van Oosterwijk JG, van Ruler MA, Briaire-de Bruijn IH, Herpers B, Gelderblom H, van de Water B, Bovée JV.
van Oosterwijk JG, et al. Among authors: van ruler ma.
Br J Cancer. 2013 Sep 3;109(5):1214-22. doi: 10.1038/bjc.2013.451. Epub 2013 Aug 6.
Br J Cancer. 2013.
PMID: 23922104
Free PMC article.
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Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.
van Oosterwijk JG, Meijer D, van Ruler MA, van den Akker BE, Oosting J, Krenács T, Picci P, Flanagan AM, Liegl-Atzwanger B, Leithner A, Athanasou N, Daugaard S, Hogendoorn PC, Bovée JV.
van Oosterwijk JG, et al. Among authors: van ruler ma.
Am J Pathol. 2013 Apr;182(4):1347-56. doi: 10.1016/j.ajpath.2012.12.036. Epub 2013 Feb 15.
Am J Pathol. 2013.
PMID: 23415961
Free article.
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BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors.
Boeuf S, Bovée JV, Lehner B, van den Akker B, van Ruler M, Cleton-Jansen AM, Richter W.
Boeuf S, et al.
BMC Cancer. 2012 Oct 22;12:488. doi: 10.1186/1471-2407-12-488.
BMC Cancer. 2012.
PMID: 23088614
Free PMC article.
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Clinical outcomes of definitive chemoradiotherapy using carboplatin and paclitaxel in esophageal cancer.
van Ruler MA, Peters FP, Slingerland M, Fiocco M, Grootenboers DA, Vulink AJ, Marijnen CA, Neelis KJ.
van Ruler MA, et al.
Dis Esophagus. 2017 Apr 1;30(4):1-9. doi: 10.1093/dote/dow033.
Dis Esophagus. 2017.
PMID: 28375477
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