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Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms.
Francis HL, Demorrow S, Franchitto A, Venter JK, Mancinelli RA, White MA, Meng F, Ueno Y, Carpino G, Renzi A, Baker KK, Shine HE, Francis TC, Gaudio E, Alpini GD, Onori P. Francis HL, et al. Among authors: meng f. Lab Invest. 2012 Feb;92(2):282-94. doi: 10.1038/labinvest.2011.158. Epub 2011 Nov 7. Lab Invest. 2012. PMID: 22064319 Free PMC article.
H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo.
Francis H, Onori P, Gaudio E, Franchitto A, DeMorrow S, Venter J, Kopriva S, Carpino G, Mancinelli R, White M, Meng F, Vetuschi A, Sferra R, Alpini G. Francis H, et al. Among authors: meng f. Mol Cancer Res. 2009 Oct;7(10):1704-13. doi: 10.1158/1541-7786.MCR-09-0261. Epub 2009 Oct 13. Mol Cancer Res. 2009. PMID: 19825989 Free PMC article.
Neuropeptide Y inhibits cholangiocarcinoma cell growth and invasion.
DeMorrow S, Onori P, Venter J, Invernizzi P, Frampton G, White M, Franchitto A, Kopriva S, Bernuzzi F, Francis H, Coufal M, Glaser S, Fava G, Meng F, Alvaro D, Carpino G, Gaudio E, Alpini G. DeMorrow S, et al. Among authors: meng f. Am J Physiol Cell Physiol. 2011 May;300(5):C1078-89. doi: 10.1152/ajpcell.00358.2010. Epub 2011 Jan 26. Am J Physiol Cell Physiol. 2011. PMID: 21270292 Free PMC article.
Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1.
Alpini G, Franchitto A, Demorrow S, Onori P, Gaudio E, Wise C, Francis H, Venter J, Kopriva S, Mancinelli R, Carpino G, Stagnitti F, Ueno Y, Han Y, Meng F, Glaser S. Alpini G, et al. Among authors: meng f. Hepatology. 2011 Feb;53(2):628-39. doi: 10.1002/hep.24041. Epub 2011 Jan 3. Hepatology. 2011. PMID: 21274883 Free PMC article.
6,546 results