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A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.
Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, Hokanson JE, Murray T, Hetmanski JB, Pillai SG, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Silverman EK; ICGN Investigators; ECLIPSE Investigators; COPDGene Investigators. Cho MH, et al. Among authors: calverley pm. Hum Mol Genet. 2012 Feb 15;21(4):947-57. doi: 10.1093/hmg/ddr524. Epub 2011 Nov 11. Hum Mol Genet. 2012. PMID: 22080838 Free PMC article.
Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema.
Hersh CP, Hansel NN, Barnes KC, Lomas DA, Pillai SG, Coxson HO, Mathias RA, Rafaels NM, Wise RA, Connett JE, Klanderman BJ, Jacobson FL, Gill R, Litonjua AA, Sparrow D, Reilly JJ, Silverman EK; ICGN Investigators. Hersh CP, et al. Am J Respir Cell Mol Biol. 2009 Sep;41(3):324-31. doi: 10.1165/rcmb.2008-0427OC. Epub 2009 Jan 8. Am J Respir Cell Mol Biol. 2009. PMID: 19131638 Free PMC article.
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.
Pillai SG, Ge D, Zhu G, Kong X, Shianna KV, Need AC, Feng S, Hersh CP, Bakke P, Gulsvik A, Ruppert A, Lødrup Carlsen KC, Roses A, Anderson W, Rennard SI, Lomas DA, Silverman EK, Goldstein DB; ICGN Investigators. Pillai SG, et al. PLoS Genet. 2009 Mar;5(3):e1000421. doi: 10.1371/journal.pgen.1000421. Epub 2009 Mar 20. PLoS Genet. 2009. PMID: 19300482 Free PMC article.
Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.
Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EF, Scholand MB, Coon H, Hoidal J, Silverman EK. Hersh CP, et al. Among authors: calverley pm. Am J Respir Crit Care Med. 2010 Sep 1;182(5):605-13. doi: 10.1164/rccm.200910-1586OC. Epub 2010 May 12. Am J Respir Crit Care Med. 2010. PMID: 20463177 Free PMC article.
α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts.
Sørheim IC, Bakke P, Gulsvik A, Pillai SG, Johannessen A, Gaarder PI, Campbell EJ, Agustí A, Calverley PM, Donner CF, Make BJ, Rennard SI, Vestbo J, Wouters EF, Paré PD, Levy RD, Coxson HO, Lomas DA, Hersh CP, Silverman EK. Sørheim IC, et al. Among authors: calverley pm. Chest. 2010 Nov;138(5):1125-32. doi: 10.1378/chest.10-0746. Epub 2010 Jul 1. Chest. 2010. PMID: 20595457 Free PMC article.
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
Kim DK, Cho MH, Hersh CP, Lomas DA, Miller BE, Kong X, Bakke P, Gulsvik A, Agustí A, Wouters E, Celli B, Coxson H, Vestbo J, MacNee W, Yates JC, Rennard S, Litonjua A, Qiu W, Beaty TH, Crapo JD, Riley JH, Tal-Singer R, Silverman EK; ECLIPSE, ICGN, and COPDGene Investigators. Kim DK, et al. Am J Respir Crit Care Med. 2012 Dec 15;186(12):1238-47. doi: 10.1164/rccm.201206-1013OC. Epub 2012 Nov 9. Am J Respir Crit Care Med. 2012. PMID: 23144326 Free PMC article. Clinical Trial.
Lessons from ECLIPSE: a review of COPD biomarkers.
Faner R, Tal-Singer R, Riley JH, Celli B, Vestbo J, MacNee W, Bakke P, Calverley PM, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, Miller BE, Rennard SI, Wouters EF, Yates JC, Silverman EK, Agusti A; ECLIPSE Study Investigators. Faner R, et al. Among authors: calverley pm. Thorax. 2014 Jul;69(7):666-72. doi: 10.1136/thoraxjnl-2013-204778. Epub 2013 Dec 5. Thorax. 2014. PMID: 24310110 Review.
Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease.
McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard SI, Wouters EF, Bakke P, Tal-Singer R, Miller BE, Gulsvik A, Casaburi R, Wells JM, Regan EA, Make BJ, Hokanson JE, Lange C, Crapo JD, Beaty TH, Silverman EK, Hersh CP; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints and COPDGene Investigators. McDonald ML, et al. Among authors: calverley pm. Am J Respir Cell Mol Biol. 2014 Nov;51(5):678-87. doi: 10.1165/rcmb.2014-0135OC. Am J Respir Cell Mol Biol. 2014. PMID: 24825563 Free PMC article. Clinical Trial.
Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.
Qiao D, Ameli A, Prokopenko D, Chen H, Kho AT, Parker MM, Morrow J, Hobbs BD, Liu Y, Beaty TH, Crapo JD, Barnes KC, Nickerson DA, Bamshad M, Hersh CP, Lomas DA, Agusti A, Make BJ, Calverley PMA, Donner CF, Wouters EF, Vestbo J, Paré PD, Levy RD, Rennard SI, Tal-Singer R, Spitz MR, Sharma A, Ruczinski I, Lange C, Silverman EK, Cho MH. Qiao D, et al. Hum Mol Genet. 2018 Nov 1;27(21):3801-3812. doi: 10.1093/hmg/ddy269. Hum Mol Genet. 2018. PMID: 30060175 Free PMC article.
458 results