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A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.
Yokoyama S, Woods SL, Boyle GM, Aoude LG, MacGregor S, Zismann V, Gartside M, Cust AE, Haq R, Harland M, Taylor JC, Duffy DL, Holohan K, Dutton-Regester K, Palmer JM, Bonazzi V, Stark MS, Symmons J, Law MH, Schmidt C, Lanagan C, O'Connor L, Holland EA, Schmid H, Maskiell JA, Jetann J, Ferguson M, Jenkins MA, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Hopper JL, Whiteman DC, Pharoah PD, Easton DF, Dunning AM, Newton-Bishop JA, Montgomery GW, Martin NG, Mann GJ, Bishop DT, Tsao H, Trent JM, Fisher DE, Hayward NK, Brown KM. Yokoyama S, et al. Nature. 2011 Nov 13;480(7375):99-103. doi: 10.1038/nature10630. Nature. 2011. PMID: 22080950 Free PMC article.
MITF pathway mutations in melanoma.
Yokoyama S, Salma N, Fisher DE. Yokoyama S, et al. Pigment Cell Melanoma Res. 2009 Aug;22(4):376-7. doi: 10.1111/j.1755-148X.2009.00599.x. Epub 2009 Jun 25. Pigment Cell Melanoma Res. 2009. PMID: 19558635 No abstract available.
Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.
Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, Frederick DT, Hurley AD, Nellore A, Kung AL, Wargo JA, Song JS, Fisher DE, Arany Z, Widlund HR. Haq R, et al. Among authors: yokoyama s. Cancer Cell. 2013 Mar 18;23(3):302-15. doi: 10.1016/j.ccr.2013.02.003. Epub 2013 Mar 7. Cancer Cell. 2013. PMID: 23477830 Free PMC article.
Lineage-specific transcriptional regulation of DICER by MITF in melanocytes.
Levy C, Khaled M, Robinson KC, Veguilla RA, Chen PH, Yokoyama S, Makino E, Lu J, Larue L, Beermann F, Chin L, Bosenberg M, Song JS, Fisher DE. Levy C, et al. Among authors: yokoyama s. Cell. 2010 Jun 11;141(6):994-1005. doi: 10.1016/j.cell.2010.05.004. Cell. 2010. PMID: 20550935 Free PMC article.
BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.
Haq R, Yokoyama S, Hawryluk EB, Jönsson GB, Frederick DT, McHenry K, Porter D, Tran TN, Love KT, Langer R, Anderson DG, Garraway LA, Duncan LM, Morton DL, Hoon DS, Wargo JA, Song JS, Fisher DE. Haq R, et al. Among authors: yokoyama s. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4321-6. doi: 10.1073/pnas.1205575110. Epub 2013 Feb 27. Proc Natl Acad Sci U S A. 2013. PMID: 23447565 Free PMC article.
MYO5A Gene Is a Target of MITF in Melanocytes.
Alves CP, Yokoyama S, Goedert L, Pontes CLS, Sousa JF, Fisher DE, Espreafico EM. Alves CP, et al. Among authors: yokoyama s. J Invest Dermatol. 2017 Apr;137(4):985-989. doi: 10.1016/j.jid.2016.11.026. Epub 2016 Dec 6. J Invest Dermatol. 2017. PMID: 27939378 Free article. No abstract available.
Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.
Feige E, Yokoyama S, Levy C, Khaled M, Igras V, Lin RJ, Lee S, Widlund HR, Granter SR, Kung AL, Fisher DE. Feige E, et al. Among authors: yokoyama s. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E924-33. doi: 10.1073/pnas.1106351108. Epub 2011 Sep 26. Proc Natl Acad Sci U S A. 2011. PMID: 21949374 Free PMC article.
SOX10 Regulates Melanoma Immunogenicity through an IRF4-IRF1 Axis.
Yokoyama S, Takahashi A, Kikuchi R, Nishibu S, Lo JA, Hejna M, Moon WM, Kato S, Zhou Y, Hodi FS, Song JS, Sakurai H, Fisher DE, Hayakawa Y. Yokoyama S, et al. Cancer Res. 2021 Dec 15;81(24):6131-6141. doi: 10.1158/0008-5472.CAN-21-2078. Epub 2021 Nov 2. Cancer Res. 2021. PMID: 34728538 Free PMC article.
3,506 results