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Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.
Honke N, Shaabani N, Cadeddu G, Sorg UR, Zhang DE, Trilling M, Klingel K, Sauter M, Kandolf R, Gailus N, van Rooijen N, Burkart C, Baldus SE, Grusdat M, Löhning M, Hengel H, Pfeffer K, Tanaka M, Häussinger D, Recher M, Lang PA, Lang KS. Honke N, et al. Among authors: gailus n. Nat Immunol. 2011 Nov 20;13(1):51-7. doi: 10.1038/ni.2169. Nat Immunol. 2011. PMID: 22101728
Tunicamycin inhibits diabetes.
Shaabani N, Honke N, Lang PA, Görg B, Proksch P, Gailus N, Gotoh T, Häussinger D, Lang KS. Shaabani N, et al. Among authors: gailus n. Cell Physiol Biochem. 2012;29(3-4):595-602. doi: 10.1159/000338513. Epub 2012 Apr 3. Cell Physiol Biochem. 2012. PMID: 22508066 Free article.
Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice.
Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, Häussinger D, Ohashi PS, Zinkernagel RM, Lang KS. Lang PA, et al. Among authors: gailus n. Hepatology. 2010 Jul;52(1):25-32. doi: 10.1002/hep.23640. Hepatology. 2010. PMID: 20578253