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Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.
Honke N, Shaabani N, Cadeddu G, Sorg UR, Zhang DE, Trilling M, Klingel K, Sauter M, Kandolf R, Gailus N, van Rooijen N, Burkart C, Baldus SE, Grusdat M, Löhning M, Hengel H, Pfeffer K, Tanaka M, Häussinger D, Recher M, Lang PA, Lang KS. Honke N, et al. Among authors: shaabani n. Nat Immunol. 2011 Nov 20;13(1):51-7. doi: 10.1038/ni.2169. Nat Immunol. 2011. PMID: 22101728
Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses.
Honke N, Shaabani N, Merches K, Gassa A, Kraft A, Ehrhardt K, Häussinger D, Löhning M, Dittmer U, Hengel H, Recher M, Lang PA, Lang KS. Honke N, et al. Among authors: shaabani n. Eur J Immunol. 2016 Feb;46(2):372-80. doi: 10.1002/eji.201545765. Epub 2015 Nov 17. Eur J Immunol. 2016. PMID: 26507703 Free PMC article.
Tunicamycin inhibits diabetes.
Shaabani N, Honke N, Lang PA, Görg B, Proksch P, Gailus N, Gotoh T, Häussinger D, Lang KS. Shaabani N, et al. Cell Physiol Biochem. 2012;29(3-4):595-602. doi: 10.1159/000338513. Epub 2012 Apr 3. Cell Physiol Biochem. 2012. PMID: 22508066 Free article.
Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency.
Lang PA, Shaabani N, Borkens S, Honke N, Scheu S, Booth S, Brenner D, Meryk A, Barthuber C, Recher M, Mak TW, Ohashi PS, Häussinger D, Griffiths GM, Thrasher AJ, Bouma G, Lang KS. Lang PA, et al. Among authors: shaabani n. J Allergy Clin Immunol. 2013 Mar;131(3):815-24. doi: 10.1016/j.jaci.2012.08.050. Epub 2012 Nov 6. J Allergy Clin Immunol. 2013. PMID: 23141740 Free PMC article.
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.
Khairnar V, Duhan V, Maney SK, Honke N, Shaabani N, Pandyra AA, Seifert M, Pozdeev V, Xu HC, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, Westendorf AM, Häussinger D, Lang F, Dittmer U, Küppers R, Recher M, Hardt C, Scheffrahn I, Beauchemin N, Göthert JR, Singer BB, Lang PA, Lang KS. Khairnar V, et al. Among authors: shaabani n. Nat Commun. 2015 Feb 18;6:6217. doi: 10.1038/ncomms7217. Nat Commun. 2015. PMID: 25692415 Free PMC article.
57 results