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Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase.
Salvi E, Kutalik Z, Glorioso N, Benaglio P, Frau F, Kuznetsova T, Arima H, Hoggart C, Tichet J, Nikitin YP, Conti C, Seidlerova J, Tikhonoff V, Stolarz-Skrzypek K, Johnson T, Devos N, Zagato L, Guarrera S, Zaninello R, Calabria A, Stancanelli B, Troffa C, Thijs L, Rizzi F, Simonova G, Lupoli S, Argiolas G, Braga D, D'Alessio MC, Ortu MF, Ricceri F, Mercurio M, Descombes P, Marconi M, Chalmers J, Harrap S, Filipovsky J, Bochud M, Iacoviello L, Ellis J, Stanton AV, Laan M, Padmanabhan S, Dominiczak AF, Samani NJ, Melander O, Jeunemaitre X, Manunta P, Shabo A, Vineis P, Cappuccio FP, Caulfield MJ, Matullo G, Rivolta C, Munroe PB, Barlassina C, Staessen JA, Beckmann JS, Cusi D. Salvi E, et al. Among authors: d alessio mc. Hypertension. 2012 Feb;59(2):248-55. doi: 10.1161/HYPERTENSIONAHA.111.181990. Epub 2011 Dec 19. Hypertension. 2012. PMID: 22184326 Free PMC article.
Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro.
Di Simone N, Silano M, Castellani R, Di Nicuolo F, D'Alessio MC, Franceschi F, Tritarelli A, Leone AM, Tersigni C, Gasbarrini G, Silveri NG, Caruso A, Gasbarrini A. Di Simone N, et al. Among authors: d alessio mc. Am J Gastroenterol. 2010 Oct;105(10):2254-61. doi: 10.1038/ajg.2010.233. Epub 2010 Jun 22. Am J Gastroenterol. 2010. PMID: 20571491
Decreased expression of heparin-binding epidermal growth factor-like growth factor as a newly identified pathogenic mechanism of antiphospholipid-mediated defective placentation.
Di Simone N, Marana R, Castellani R, Di Nicuolo F, D'Alessio MC, Raschi E, Borghi MO, Chen PP, Sanguinetti M, Caruso A, Meroni PL. Di Simone N, et al. Among authors: d alessio mc. Arthritis Rheum. 2010 May;62(5):1504-12. doi: 10.1002/art.27361. Arthritis Rheum. 2010. PMID: 20131286 Free article.