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Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.
Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, Orešič M, Kallioniemi O, Iljin K. Vainio P, et al. Among authors: kallioniemi o. Oncotarget. 2011 Dec;2(12):1176-90. doi: 10.18632/oncotarget.397. Oncotarget. 2011. PMID: 22202492 Free PMC article.
15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K. Lehtinen L, et al. Among authors: kallioniemi o. J Pathol. 2012 Mar;226(4):674-86. doi: 10.1002/path.3956. Epub 2012 Jan 17. J Pathol. 2012. PMID: 22072156
Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models.
Härmä V, Knuuttila M, Virtanen J, Mirtti T, Kohonen P, Kovanen P, Happonen A, Kaewphan S, Ahonen I, Kallioniemi O, Grafström R, Lötjönen J, Nees M. Härmä V, et al. Among authors: kallioniemi o. Oncogene. 2012 Apr 19;31(16):2075-89. doi: 10.1038/onc.2011.396. Epub 2011 Sep 26. Oncogene. 2012. PMID: 21996742 Free PMC article.
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion.
Björkman M, Östling P, Härmä V, Virtanen J, Mpindi JP, Rantala J, Mirtti T, Vesterinen T, Lundin M, Sankila A, Rannikko A, Kaivanto E, Kohonen P, Kallioniemi O, Nees M. Björkman M, et al. Among authors: kallioniemi o. Oncogene. 2012 Jul 19;31(29):3444-56. doi: 10.1038/onc.2011.512. Epub 2011 Nov 28. Oncogene. 2012. PMID: 22120715
420 results