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774 results

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Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling.
Carpinelli MR, Hilton DJ, Metcalf D, Antonchuk JL, Hyland CD, Mifsud SL, Di Rago L, Hilton AA, Willson TA, Roberts AW, Ramsay RG, Nicola NA, Alexander WS. Carpinelli MR, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6553-8. doi: 10.1073/pnas.0401496101. Epub 2004 Apr 7. Proc Natl Acad Sci U S A. 2004. PMID: 15071178 Free PMC article.
A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia.
Majewski IJ, Metcalf D, Mielke LA, Krebs DL, Ellis S, Carpinelli MR, Mifsud S, Di Rago L, Corbin J, Nicola NA, Hilton DJ, Alexander WS. Majewski IJ, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14146-51. doi: 10.1073/pnas.0606439103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966598 Free PMC article.
Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene.
Alexander WS, Viney EM, Zhang JG, Metcalf D, Kauppi M, Hyland CD, Carpinelli MR, Stevenson W, Croker BA, Hilton AA, Ellis S, Selan C, Nandurkar HH, Goodnow CC, Kile BT, Nicola NA, Roberts AW, Hilton DJ. Alexander WS, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16442-7. doi: 10.1073/pnas.0607872103. Epub 2006 Oct 24. Proc Natl Acad Sci U S A. 2006. PMID: 17062753 Free PMC article.
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.
Kruse EA, Loughran SJ, Baldwin TM, Josefsson EC, Ellis S, Watson DK, Nurden P, Metcalf D, Hilton DJ, Alexander WS, Kile BT. Kruse EA, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13814-9. doi: 10.1073/pnas.0906556106. Epub 2009 Jul 31. Proc Natl Acad Sci U S A. 2009. PMID: 19666492 Free PMC article.
Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.
Stevenson WS, Hyland CD, Zhang JG, Morgan PO, Willson TA, Gill A, Hilton AA, Viney EM, Bahlo M, Masters SL, Hennebry S, Richardson SJ, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS. Stevenson WS, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16625-30. doi: 10.1073/pnas.1010390107. Epub 2010 Sep 7. Proc Natl Acad Sci U S A. 2010. PMID: 20823251 Free PMC article.
Regulation of hematopoietic stem cells by their mature progeny.
de Graaf CA, Kauppi M, Baldwin T, Hyland CD, Metcalf D, Willson TA, Carpinelli MR, Smyth GK, Alexander WS, Hilton DJ. de Graaf CA, et al. Among authors: metcalf d. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21689-94. doi: 10.1073/pnas.1016166108. Epub 2010 Nov 29. Proc Natl Acad Sci U S A. 2010. PMID: 21115812 Free PMC article.
774 results